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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYBB
All Species:
41.21
Human Site:
Y440
Identified Species:
82.42
UniProt:
P04839
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04839
NP_000388.2
570
65336
Y440
N
L
K
L
K
K
I
Y
F
Y
W
L
C
R
D
Chimpanzee
Pan troglodytes
XP_001136590
570
65247
Y440
N
L
K
L
K
K
I
Y
F
Y
W
L
C
R
D
Rhesus Macaque
Macaca mulatta
XP_001083654
570
65303
Y440
N
L
R
L
K
K
I
Y
F
Y
W
L
C
R
D
Dog
Lupus familis
XP_549136
564
65065
Y434
N
L
K
T
Q
T
I
Y
F
Y
W
I
C
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61093
570
65286
Y440
S
L
K
L
K
K
I
Y
F
Y
W
L
C
R
D
Rat
Rattus norvegicus
Q672K1
568
64398
Y438
L
P
G
L
S
K
V
Y
F
Y
W
I
C
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514075
571
65286
Y441
N
L
K
L
K
K
I
Y
F
Y
W
L
C
R
D
Chicken
Gallus gallus
NP_001093756
571
65555
Y441
N
L
K
L
K
K
I
Y
F
Y
W
L
C
R
D
Frog
Xenopus laevis
NP_001085924
570
64842
Y440
T
L
R
L
K
K
I
Y
F
Y
W
L
C
R
D
Zebra Danio
Brachydanio rerio
NP_956708
565
64471
Y438
N
V
F
T
K
K
I
Y
F
Y
W
L
C
P
E
Tiger Blowfish
Takifugu rubipres
NP_001027904
565
64536
Y438
E
V
F
T
K
K
I
Y
F
Y
W
L
C
P
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81211
948
107256
D787
D
N
E
F
S
R
S
D
F
S
W
N
S
C
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
96.6
57.8
N.A.
93.1
57.8
N.A.
88
84.4
80
68.4
68
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
97.7
71.7
N.A.
96.8
72.1
N.A.
93.3
90.1
86.8
80.5
79.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
93.3
60
N.A.
100
100
86.6
66.6
60
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
73.3
N.A.
100
100
93.3
80
73.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
92
9
0
% C
% Asp:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
67
% D
% Glu:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
25
% E
% Phe:
0
0
17
9
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
84
0
0
0
0
17
0
0
0
% I
% Lys:
0
0
50
0
75
84
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
67
0
67
0
0
0
0
0
0
0
75
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
59
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
17
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
17
0
0
9
0
0
0
0
0
0
0
75
0
% R
% Ser:
9
0
0
0
17
0
9
0
0
9
0
0
9
0
0
% S
% Thr:
9
0
0
25
0
9
0
0
0
0
0
0
0
0
9
% T
% Val:
0
17
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
92
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _