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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMY2A
All Species:
25.45
Human Site:
S493
Identified Species:
56
UniProt:
P04746
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04746
NP_000690.1
511
57707
S493
D
D
G
K
A
H
F
S
I
S
N
S
A
E
D
Chimpanzee
Pan troglodytes
NP_001103626
511
57676
S493
D
D
G
K
A
H
F
S
I
S
N
S
A
E
D
Rhesus Macaque
Macaca mulatta
XP_001109490
511
57574
S493
N
D
G
K
A
Q
F
S
I
S
N
S
A
E
D
Dog
Lupus familis
XP_537942
511
57749
S493
G
D
G
N
A
H
F
S
I
S
N
S
A
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P00687
511
57605
S493
N
D
G
K
A
H
F
S
I
S
N
S
A
E
D
Rat
Rattus norvegicus
P00689
508
57159
S490
S
D
G
K
A
H
F
S
I
S
N
S
A
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510273
510
57723
S492
K
D
G
K
A
Q
F
S
I
S
N
T
A
E
D
Chicken
Gallus gallus
NP_001001473
512
57460
Q494
S
D
G
K
A
N
F
Q
I
S
N
S
D
E
D
Frog
Xenopus laevis
NP_001089638
511
57441
Q493
G
Y
G
Y
A
R
F
Q
I
S
N
N
D
E
D
Zebra Danio
Brachydanio rerio
NP_998176
512
56860
R494
G
D
G
K
A
S
F
R
I
S
N
Q
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08144
494
53727
N476
S
D
G
R
A
S
I
N
I
G
S
S
E
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
96.2
90.4
N.A.
84.5
84.5
N.A.
83.3
82.6
78
73.2
N.A.
52.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.6
95.6
N.A.
92.1
91.7
N.A.
91.1
89.6
87.6
85.5
N.A.
67.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
86.6
N.A.
93.3
93.3
N.A.
80
73.3
53.3
66.6
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
100
93.3
N.A.
86.6
80
60
66.6
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
100
0
0
0
0
0
0
0
64
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
91
0
0
0
0
0
0
0
0
0
0
19
10
100
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
19
91
0
% E
% Phe:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% F
% Gly:
28
0
100
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
100
0
0
0
0
0
0
% I
% Lys:
10
0
0
73
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
10
0
10
0
10
0
0
91
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
19
0
19
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
28
0
0
0
0
19
0
64
0
91
10
73
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _