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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHBG
All Species:
16.36
Human Site:
S72
Identified Species:
60
UniProt:
P04278
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04278
NP_001031.2
402
43779
S72
K
I
T
K
T
S
S
S
F
E
V
R
T
W
D
Chimpanzee
Pan troglodytes
XP_511958
402
43688
S72
K
I
T
K
T
S
S
S
F
E
V
R
T
W
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536625
405
43987
S73
K
I
K
K
S
S
S
S
F
E
L
R
T
W
D
Cat
Felis silvestris
Mouse
Mus musculus
P97497
403
44798
S73
K
I
S
K
P
H
S
S
F
E
F
R
T
W
D
Rat
Rattus norvegicus
P08689
403
44515
S73
K
I
S
K
P
S
S
S
F
E
F
R
T
W
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515036
281
30657
L18
R
A
T
S
Y
F
D
L
R
T
W
D
P
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088520
409
45087
P73
F
E
V
R
T
F
D
P
E
G
V
L
L
F
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
75.8
N.A.
66.5
67.4
N.A.
33
N.A.
32.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
N.A.
84.6
N.A.
76.4
77.4
N.A.
46.7
N.A.
50.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
80
N.A.
73.3
80
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
80
86.6
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
29
0
0
0
0
15
0
0
72
% D
% Glu:
0
15
0
0
0
0
0
0
15
72
0
0
0
15
0
% E
% Phe:
15
0
0
0
0
29
0
0
72
0
29
0
0
15
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
29
% G
% His:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
72
0
15
72
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
15
0
0
15
15
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
29
0
0
15
0
0
0
0
15
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
15
0
0
0
0
15
0
0
72
0
0
0
% R
% Ser:
0
0
29
15
15
58
72
72
0
0
0
0
0
0
0
% S
% Thr:
0
0
43
0
43
0
0
0
0
15
0
0
72
0
0
% T
% Val:
0
0
15
0
0
0
0
0
0
0
43
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
0
0
72
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _