KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD3D
All Species:
18.18
Human Site:
T139
Identified Species:
44.44
UniProt:
P04234
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04234
NP_000723.1
171
18930
T139
R
L
S
G
A
A
D
T
Q
A
L
L
R
N
D
Chimpanzee
Pan troglodytes
XP_508789
171
18932
T139
R
L
S
G
A
A
D
T
Q
A
L
L
R
N
D
Rhesus Macaque
Macaca mulatta
XP_001097302
171
18973
T139
R
L
S
G
A
A
D
T
Q
A
L
L
R
N
D
Dog
Lupus familis
XP_536556
171
19274
T139
R
S
S
K
S
A
D
T
Q
I
L
L
E
N
D
Cat
Felis silvestris
Mouse
Mus musculus
P04235
173
19013
V139
R
P
S
G
A
A
E
V
Q
A
L
L
K
N
E
Rat
Rattus norvegicus
P19377
173
19338
T139
R
L
S
G
A
V
D
T
Q
V
L
L
K
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519836
169
18782
K137
R
T
S
R
A
S
D
K
Q
T
L
L
P
N
D
Chicken
Gallus gallus
Q98910
175
19043
S138
Q
S
R
A
A
A
G
S
R
P
R
A
Q
K
M
Frog
Xenopus laevis
NP_001079051
167
18878
A136
G
S
E
T
R
R
P
A
R
A
S
D
K
Q
N
Zebra Danio
Brachydanio rerio
NP_001093573
115
12960
R86
K
L
Q
Q
T
S
M
R
A
K
P
I
E
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
93.5
69.5
N.A.
63.5
68.2
N.A.
42.1
25.1
38
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
97.6
83
N.A.
76.8
80.3
N.A.
67.2
42.8
54.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
66.6
73.3
N.A.
60
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
66.6
40
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
70
60
0
10
10
50
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
60
0
0
0
0
10
0
0
50
% D
% Glu:
0
0
10
0
0
0
10
0
0
0
0
0
20
0
30
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
50
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
10
0
10
0
0
30
10
0
% K
% Leu:
0
50
0
0
0
0
0
0
0
0
70
70
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
10
% N
% Pro:
0
10
0
0
0
0
10
0
0
10
10
0
10
0
0
% P
% Gln:
10
0
10
10
0
0
0
0
70
0
0
0
10
10
0
% Q
% Arg:
70
0
10
10
10
10
0
10
20
0
10
0
30
0
0
% R
% Ser:
0
30
70
0
10
20
0
10
0
0
10
0
0
0
0
% S
% Thr:
0
10
0
10
10
0
0
50
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
10
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _