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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLKB1
All Species:
16.36
Human Site:
S455
Identified Species:
40
UniProt:
P03952
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P03952
NP_000883.2
638
71370
S455
Y
S
G
I
L
N
L
S
D
I
T
K
D
T
P
Chimpanzee
Pan troglodytes
XP_001165806
629
70378
S456
Y
S
G
I
L
N
Q
S
E
I
K
E
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001090398
900
99753
S578
Y
I
G
I
L
N
Q
S
E
I
K
E
D
T
S
Dog
Lupus familis
XP_532838
629
70133
T451
I
L
N
L
S
E
I
T
K
E
T
P
F
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P26262
638
71350
S455
Y
G
G
I
L
S
L
S
E
I
T
K
E
T
P
Rat
Rattus norvegicus
P14272
638
71255
S455
Y
G
G
I
L
N
L
S
E
I
T
N
K
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519233
360
39589
F186
M
A
C
L
R
D
I
F
S
E
T
A
F
A
D
Chicken
Gallus gallus
XP_420678
663
75784
K490
R
V
Y
A
G
V
L
K
Q
S
E
I
N
E
N
Frog
Xenopus laevis
NP_001086768
629
69781
V454
W
I
I
Y
S
G
F
V
R
I
L
N
I
T
K
Zebra Danio
Brachydanio rerio
XP_002666698
696
77438
N522
Y
M
G
M
R
V
M
N
S
V
S
N
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.9
37.1
79.4
N.A.
76.1
74.9
N.A.
29.9
55
47.3
25.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.8
51
88.4
N.A.
86.8
86.2
N.A.
39.6
70.8
66.9
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
60
6.6
N.A.
73.3
73.3
N.A.
6.6
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
73.3
33.3
N.A.
93.3
80
N.A.
33.3
13.3
20
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
0
0
10
10
20
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
0
0
0
30
0
10
% D
% Glu:
0
0
0
0
0
10
0
0
40
20
10
20
10
10
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
0
20
0
0
% F
% Gly:
0
20
60
0
10
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
20
10
50
0
0
20
0
0
60
0
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
10
0
20
20
10
0
10
% K
% Leu:
0
10
0
20
50
0
40
0
0
0
10
0
0
0
0
% L
% Met:
10
10
0
10
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
40
0
10
0
0
0
30
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
30
% P
% Gln:
0
0
0
0
0
0
20
0
10
0
0
0
0
0
10
% Q
% Arg:
10
0
0
0
20
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
20
0
0
20
10
0
50
20
10
10
0
0
10
20
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
50
0
0
60
0
% T
% Val:
0
10
0
0
0
20
0
10
0
10
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
60
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _