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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC4A1
All Species:
25.15
Human Site:
Y278
Identified Species:
69.17
UniProt:
P02730
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02730
NP_000333.1
911
101792
Y278
P
E
A
P
H
I
D
Y
T
Q
L
G
R
A
A
Chimpanzee
Pan troglodytes
XP_511548
900
100325
F245
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
Rhesus Macaque
Macaca mulatta
XP_001103478
1172
130022
Y500
P
S
S
A
N
M
D
Y
H
E
I
G
R
S
I
Dog
Lupus familis
XP_532761
1223
134633
Y564
P
S
S
A
N
M
D
Y
H
E
I
G
R
S
I
Cat
Felis silvestris
Mouse
Mus musculus
P04919
929
103117
Y291
P
E
A
P
H
V
D
Y
T
Q
L
G
R
A
A
Rat
Rattus norvegicus
P23562
927
103154
Y291
P
E
A
P
H
I
D
Y
T
Q
L
G
R
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P15575
922
102205
Y285
P
D
S
P
R
L
S
Y
H
E
I
R
R
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107912
1232
137883
Y568
P
P
S
T
N
M
D
Y
H
Q
I
G
R
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791964
1247
140119
Y562
P
T
H
S
D
I
N
Y
H
E
L
G
R
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
49.3
45.7
N.A.
81.3
81.4
N.A.
N.A.
61.8
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
36.4
Protein Similarity:
100
93
62.8
58.5
N.A.
88.1
89.2
N.A.
N.A.
74.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
100
33.3
33.3
33.3
N.A.
93.3
100
N.A.
N.A.
40
N.A.
40
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
53.3
73.3
73.3
N.A.
100
100
N.A.
N.A.
73.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
23
0
0
0
0
0
0
0
0
0
56
56
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
12
0
67
0
0
0
0
0
0
0
0
% D
% Glu:
0
45
0
0
0
0
0
0
0
45
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
78
0
0
0
% G
% His:
0
0
12
0
34
0
0
0
56
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
34
0
0
0
0
45
0
0
0
34
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
0
23
0
0
0
0
56
0
0
0
0
% L
% Met:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
34
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
89
12
0
56
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
45
0
12
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
12
0
12
89
0
0
% R
% Ser:
0
23
45
12
0
0
12
0
0
0
0
0
0
45
0
% S
% Thr:
0
12
0
12
0
0
0
0
34
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
12
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _