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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LDLR
All Species:
26.67
Human Site:
Y845
Identified Species:
65.19
UniProt:
P01130
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01130
NP_000518.1
860
95376
Y845
I
C
H
N
Q
D
G
Y
S
Y
P
S
R
Q
M
Chimpanzee
Pan troglodytes
XP_001167447
860
95392
Y845
I
C
R
N
Q
D
G
Y
S
Y
P
S
R
Q
M
Rhesus Macaque
Macaca mulatta
NP_001028078
853
94759
Y838
I
C
R
N
Q
D
G
Y
S
Y
P
S
R
Q
M
Dog
Lupus familis
XP_546704
1149
124413
T1069
D
E
L
H
I
G
R
T
A
Q
I
G
H
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
P35951
864
95116
Y849
I
C
R
S
Q
D
G
Y
T
Y
P
S
R
Q
M
Rat
Rattus norvegicus
P35952
879
96603
Y864
I
C
R
S
Q
D
G
Y
T
Y
P
S
R
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510419
931
103761
Y916
I
C
K
S
Q
D
G
Y
T
Y
P
S
R
Q
I
Chicken
Gallus gallus
Q98931
917
101361
T896
D
E
I
H
I
G
R
T
A
Q
I
G
H
V
Y
Frog
Xenopus laevis
Q99087
909
101277
Y894
I
C
R
S
Q
D
G
Y
T
Y
P
S
R
Q
M
Zebra Danio
Brachydanio rerio
NP_957217
866
95790
A847
I
D
I
S
R
H
S
A
S
V
G
H
T
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
93.4
40.2
N.A.
77.5
75.5
N.A.
66.6
51.5
63.1
50.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
95.6
52.3
N.A.
85.5
83.7
N.A.
77.4
65.3
73.8
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
80
80
N.A.
73.3
0
80
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
93.3
93.3
N.A.
93.3
13.3
93.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
20
0
0
0
0
0
0
% A
% Cys:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
10
0
0
0
70
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
20
70
0
0
0
10
20
0
0
0
% G
% His:
0
0
10
20
0
10
0
0
0
0
0
10
20
0
0
% H
% Ile:
80
0
20
0
20
0
0
0
0
0
20
0
0
0
10
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% M
% Asn:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
10
% P
% Gln:
0
0
0
0
70
0
0
0
0
20
0
0
0
70
0
% Q
% Arg:
0
0
50
0
10
0
20
0
0
0
0
0
70
0
0
% R
% Ser:
0
0
0
50
0
0
10
0
40
0
0
70
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
20
40
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
70
0
0
0
10
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _