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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
A2M
All Species:
13.94
Human Site:
Y449
Identified Species:
43.81
UniProt:
P01023
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01023
NP_000005.2
1474
163292
Y449
E
E
A
H
H
T
A
Y
L
V
F
S
P
S
K
Chimpanzee
Pan troglodytes
XP_001139488
1474
163224
Y449
E
E
A
H
H
T
A
Y
L
V
F
S
P
S
K
Rhesus Macaque
Macaca mulatta
XP_001114328
1474
163644
Y449
E
E
A
H
H
T
A
Y
L
V
F
S
P
S
K
Dog
Lupus familis
XP_534893
2036
228449
N1010
K
E
A
D
H
T
A
N
L
V
F
S
L
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQT1
1474
164308
N455
V
E
A
W
H
T
A
N
A
V
F
S
P
S
R
Rat
Rattus norvegicus
P06238
1472
163767
Y452
V
E
A
W
H
T
A
Y
A
V
F
S
P
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519533
1262
139002
T267
Y
G
K
P
V
P
G
T
V
T
W
S
V
C
R
Chicken
Gallus gallus
P20740
1473
166336
V455
Y
P
D
A
S
L
S
V
Q
R
L
Y
S
W
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.9
58.2
N.A.
72.4
73.8
N.A.
54.2
45.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.9
64.8
N.A.
84.1
85
N.A.
67.5
64.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
66.6
73.3
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
73.3
80
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
75
13
0
0
75
0
25
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
38
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
38
75
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
13
0
0
0
0
0
0
0
0
0
0
0
50
% K
% Leu:
0
0
0
0
0
13
0
0
50
0
13
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
13
0
13
0
0
0
0
0
0
63
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
38
% R
% Ser:
0
0
0
0
13
0
13
0
0
0
0
88
13
75
0
% S
% Thr:
0
0
0
0
0
75
0
13
0
13
0
0
0
0
13
% T
% Val:
25
0
0
0
13
0
0
13
13
75
0
0
13
0
0
% V
% Trp:
0
0
0
25
0
0
0
0
0
0
13
0
0
13
0
% W
% Tyr:
25
0
0
0
0
0
0
50
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _