KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F12
All Species:
13.33
Human Site:
S533
Identified Species:
36.67
UniProt:
P00748
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00748
NP_000496.2
615
67818
S533
F
L
S
L
E
R
C
S
A
P
D
V
H
G
S
Chimpanzee
Pan troglodytes
XP_518130
615
67857
S533
F
L
S
L
E
R
C
S
A
P
D
V
H
G
S
Rhesus Macaque
Macaca mulatta
P12545
810
90237
N730
V
I
E
N
K
V
C
N
R
Y
E
F
L
N
G
Dog
Lupus familis
XP_546206
611
67017
S529
L
I
P
P
Q
R
C
S
A
P
E
V
H
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R098
653
70549
S566
L
V
A
D
H
K
C
S
S
P
E
V
Y
G
A
Rat
Rattus norvegicus
P19637
559
62885
T475
L
Y
P
S
S
R
C
T
S
Q
H
L
F
N
K
Wallaby
Macropus eugenll
O18783
806
90963
N726
V
I
D
N
R
V
C
N
R
H
E
Y
L
N
G
Platypus
Ornith. anatinus
XP_001517640
436
48119
D356
H
G
A
K
I
S
P
D
M
L
C
A
G
Y
L
Chicken
Gallus gallus
P15120
434
49381
D354
Y
D
S
T
R
V
T
D
N
M
V
C
A
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
25.3
73.1
N.A.
40.7
31.5
24.4
44.3
27.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
37.9
82.2
N.A.
55.1
45.2
37.5
54.1
39.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
53.3
N.A.
33.3
13.3
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
80
N.A.
80
33.3
26.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
0
0
0
0
0
34
0
0
12
12
0
23
% A
% Cys:
0
0
0
0
0
0
78
0
0
0
12
12
0
0
0
% C
% Asp:
0
12
12
12
0
0
0
23
0
0
23
0
0
0
12
% D
% Glu:
0
0
12
0
23
0
0
0
0
0
45
0
0
0
0
% E
% Phe:
23
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
0
0
12
56
23
% G
% His:
12
0
0
0
12
0
0
0
0
12
12
0
34
0
0
% H
% Ile:
0
34
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
12
12
0
0
0
0
0
0
0
0
12
% K
% Leu:
34
23
0
23
0
0
0
0
0
12
0
12
23
0
12
% L
% Met:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% M
% Asn:
0
0
0
23
0
0
0
23
12
0
0
0
0
34
0
% N
% Pro:
0
0
23
12
0
0
12
0
0
45
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
23
45
0
0
23
0
0
0
0
0
0
% R
% Ser:
0
0
34
12
12
12
0
45
23
0
0
0
0
0
23
% S
% Thr:
0
0
0
12
0
0
12
12
0
0
0
0
0
0
0
% T
% Val:
23
12
0
0
0
34
0
0
0
0
12
45
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
12
0
0
0
0
0
0
0
12
0
12
12
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _