KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F10
All Species:
6.17
Human Site:
S485
Identified Species:
13.58
UniProt:
P00742
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00742
NP_000495.1
488
54732
S485
A
P
E
V
I
T
S
S
P
L
K
_
_
_
_
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
T458
V
N
W
I
K
E
K
T
K
L
T
_
_
_
_
Rhesus Macaque
Macaca mulatta
NP_001098054
488
54823
S485
A
P
E
A
S
T
S
S
P
L
K
_
_
_
_
Dog
Lupus familis
XP_534191
486
53473
Cat
Felis silvestris
Mouse
Mus musculus
O88947
481
53999
Rat
Rattus norvegicus
Q63207
482
54247
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001121086
469
52177
M463
L
S
W
I
K
R
M
M
R
Q
K
A
G
Q
_
Chicken
Gallus gallus
P25155
475
53123
M472
L
R
W
V
R
T
V
M
R
Q
K
_
_
_
_
Frog
Xenopus laevis
NP_001083161
462
52021
K458
R
F
L
K
S
V
L
K
K
Y
P
L
_
_
_
Zebra Danio
Brachydanio rerio
NP_958870
474
53562
T465
G
E
I
R
R
L
H
T
G
L
Q
I
H
H
V
Tiger Blowfish
Takifugu rubipres
NP_001027783
475
53756
I470
L
K
R
H
Y
G
P
I
R
R
I
V
G
_
_
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
93.6
74.8
N.A.
75.1
74.5
N.A.
64.1
54.2
53.4
45.9
43.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.4
96.7
84.8
N.A.
83.8
85
N.A.
76
69.6
68.4
62.5
62.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
9
81.8
0
N.A.
0
0
N.A.
7.1
27.2
0
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
27.2
81.8
0
N.A.
0
0
N.A.
21.4
27.2
0
26.6
7.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
19
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
0
10
0
0
0
19
0
0
% G
% His:
0
0
0
10
0
0
10
0
0
0
0
0
10
10
0
% H
% Ile:
0
0
10
19
10
0
0
10
0
0
10
10
0
0
0
% I
% Lys:
0
10
0
10
19
0
10
10
19
0
37
0
0
0
0
% K
% Leu:
28
0
10
0
0
10
10
0
0
37
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
19
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
19
0
0
0
0
10
0
19
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
19
10
0
0
10
0
% Q
% Arg:
10
10
10
10
19
10
0
0
28
10
0
0
0
0
0
% R
% Ser:
0
10
0
0
19
0
19
19
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
28
0
19
0
0
10
0
0
0
0
% T
% Val:
10
0
0
19
0
10
10
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
37
46
55
64
% _