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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F10 All Species: 7.88
Human Site: S389 Identified Species: 17.33
UniProt: P00742 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00742 NP_000495.1 488 54732 S389 V P Y V D R N S C K L S S S F
Chimpanzee Pan troglodytes Q95ND7 461 51746 K362 G W G R V F H K G R S A L V L
Rhesus Macaque Macaca mulatta NP_001098054 488 54823 S389 V P Y V D R N S C K L S S S F
Dog Lupus familis XP_534191 486 53473 P388 T L K M M E V P Y V D R N T C
Cat Felis silvestris
Mouse Mus musculus O88947 481 53999 D383 M L E V P Y V D R N T C K L S
Rat Rattus norvegicus Q63207 482 54247 D384 M M E V P Y V D R N T C R L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001121086 469 52177 K367 G F G R V H E K G R P S T V L
Chicken Gallus gallus P25155 475 53123 A376 G F G R E F E A G R L S K R L
Frog Xenopus laevis NP_001083161 462 52021 G362 F G R L Q E R G R Q A S Y L Q
Zebra Danio Brachydanio rerio NP_958870 474 53562 D369 R V L M Q Q D D G L V S G F G
Tiger Blowfish Takifugu rubipres NP_001027783 475 53756 T374 I P Y V E R R T C M E S T S L
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.8 93.6 74.8 N.A. 75.1 74.5 N.A. 64.1 54.2 53.4 45.9 43.2 N.A. N.A. N.A. N.A.
Protein Similarity: 100 61.4 96.7 84.8 N.A. 83.8 85 N.A. 76 69.6 68.4 62.5 62.3 N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 0 N.A. 6.6 6.6 N.A. 6.6 13.3 6.6 6.6 46.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 20 N.A. 13.3 13.3 N.A. 20 33.3 20 33.3 73.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 28 0 0 19 0 0 10 % C
% Asp: 0 0 0 0 19 0 10 28 0 0 10 0 0 0 0 % D
% Glu: 0 0 19 0 19 19 19 0 0 0 10 0 0 0 0 % E
% Phe: 10 19 0 0 0 19 0 0 0 0 0 0 0 10 19 % F
% Gly: 28 10 28 0 0 0 0 10 37 0 0 0 10 0 10 % G
% His: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 19 0 19 0 0 19 0 0 % K
% Leu: 0 19 10 10 0 0 0 0 0 10 28 0 10 28 37 % L
% Met: 19 10 0 19 10 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 19 0 0 19 0 0 10 0 0 % N
% Pro: 0 28 0 0 19 0 0 10 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 19 10 0 0 0 10 0 0 0 0 10 % Q
% Arg: 10 0 10 28 0 28 19 0 28 28 0 10 10 10 0 % R
% Ser: 0 0 0 0 0 0 0 19 0 0 10 64 19 28 19 % S
% Thr: 10 0 0 0 0 0 0 10 0 0 19 0 19 10 0 % T
% Val: 19 10 0 46 19 0 28 0 0 10 10 0 0 19 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 28 0 0 19 0 0 10 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _