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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
21.52
Human Site:
Y497
Identified Species:
39.44
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
Y497
A
S
L
L
Q
A
G
Y
K
G
R
V
T
G
W
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
S350
N
I
F
L
K
F
G
S
G
Y
V
S
G
W
G
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
Y502
A
S
L
F
Q
A
G
Y
K
G
R
V
T
G
W
Dog
Lupus familis
XP_855946
493
54567
K382
G
F
G
K
T
H
E
K
G
R
P
S
T
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
Y494
T
S
L
L
R
A
G
Y
K
G
R
V
T
G
W
Rat
Rattus norvegicus
P18292
617
70393
Y493
T
S
L
L
Q
A
G
Y
K
G
R
V
T
G
W
Wallaby
Macropus eugenll
O18783
806
90963
H636
Y
K
V
I
L
G
L
H
R
E
V
N
P
E
S
Platypus
Ornith. anatinus
XP_001511876
701
76014
Y578
Q
R
L
M
L
S
G
Y
K
G
R
V
T
G
W
Chicken
Gallus gallus
P25155
475
53123
S364
E
V
L
M
N
Q
K
S
G
M
V
S
G
F
G
Frog
Xenopus laevis
NP_001086517
607
69214
Y482
V
K
L
L
S
A
G
Y
K
G
R
V
T
G
W
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
N413
L
R
E
S
W
T
S
N
P
S
N
L
P
A
V
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
F491
R
M
L
M
T
T
G
F
K
G
R
V
T
G
W
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
M835
K
M
L
L
Q
P
D
M
M
G
R
V
T
G
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
13.3
93.3
6.6
N.A.
86.6
93.3
0
66.6
6.6
80
0
60
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
20
93.3
6.6
N.A.
93.3
93.3
26.6
80
13.3
80
6.6
73.3
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
39
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
8
0
0
8
0
0
0
8
0
% E
% Phe:
0
8
8
8
0
8
0
8
0
0
0
0
0
8
0
% F
% Gly:
8
0
8
0
0
8
62
0
24
62
0
0
16
62
16
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
16
0
8
8
0
8
8
54
0
0
0
0
0
0
% K
% Leu:
8
0
70
47
16
0
8
0
0
0
0
8
0
0
8
% L
% Met:
0
16
0
24
0
0
0
8
8
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
8
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
8
0
8
0
16
0
0
% P
% Gln:
8
0
0
0
31
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
16
0
0
8
0
0
0
8
8
62
0
0
0
0
% R
% Ser:
0
31
0
8
8
8
8
16
0
8
0
24
0
0
8
% S
% Thr:
16
0
0
0
16
16
0
0
0
0
0
0
70
8
0
% T
% Val:
8
8
8
0
0
0
0
0
0
0
24
62
0
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
62
% W
% Tyr:
8
0
0
0
0
0
0
47
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _