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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
13.64
Human Site:
Y448
Identified Species:
25
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
Y448
I
S
M
L
E
K
I
Y
I
H
P
R
Y
N
W
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
A308
P
H
H
N
Y
N
A
A
I
N
K
Y
N
H
D
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
Y453
I
S
M
L
E
K
I
Y
I
H
P
R
Y
N
W
Dog
Lupus familis
XP_855946
493
54567
L340
F
D
I
A
V
I
K
L
K
T
P
I
T
F
R
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
Y445
I
S
M
L
E
K
I
Y
V
H
P
R
Y
N
W
Rat
Rattus norvegicus
P18292
617
70393
Y444
I
S
M
L
E
K
I
Y
I
H
P
R
Y
N
W
Wallaby
Macropus eugenll
O18783
806
90963
H508
T
A
Q
E
P
H
R
H
T
I
F
T
P
D
T
Platypus
Ornith. anatinus
XP_001511876
701
76014
I529
I
S
G
L
E
L
I
I
I
H
P
K
Y
N
W
Chicken
Gallus gallus
P25155
475
53123
A322
F
V
H
S
K
Y
I
A
E
T
Y
D
N
D
I
Frog
Xenopus laevis
NP_001086517
607
69214
I433
I
A
L
L
E
R
I
I
V
H
P
K
Y
N
W
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
V371
L
L
H
M
K
K
P
V
V
F
T
S
E
I
H
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
I442
I
M
V
V
D
L
I
I
V
H
P
K
Y
N
W
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
F791
Q
I
I
Q
H
E
D
F
D
E
E
S
F
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
6.6
100
6.6
N.A.
93.3
100
0
73.3
6.6
60
6.6
46.6
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
100
13.3
N.A.
100
100
20
80
20
93.3
33.3
80
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
0
0
8
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
8
0
8
0
0
8
0
24
8
% D
% Glu:
0
0
0
8
47
8
0
0
8
8
8
0
8
0
0
% E
% Phe:
16
0
0
0
0
0
0
8
0
8
8
0
8
8
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
24
0
8
8
0
8
0
54
0
0
0
8
8
% H
% Ile:
54
8
16
0
0
8
62
24
39
8
0
8
0
8
8
% I
% Lys:
0
0
0
0
16
39
8
0
8
0
8
24
0
0
8
% K
% Leu:
8
8
8
47
0
16
0
8
0
0
0
0
0
0
0
% L
% Met:
0
8
31
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
8
0
0
16
54
0
% N
% Pro:
8
0
0
0
8
0
8
0
0
0
62
0
8
0
0
% P
% Gln:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
0
0
0
31
0
0
8
% R
% Ser:
0
39
0
8
0
0
0
0
0
0
0
16
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
8
16
8
8
8
0
8
% T
% Val:
0
8
8
8
8
0
0
8
31
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% W
% Tyr:
0
0
0
0
8
8
0
31
0
0
8
8
54
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _