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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
9.7
Human Site:
Y290
Identified Species:
17.78
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
Y290
F
G
Y
C
D
L
N
Y
C
E
E
A
V
E
E
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
D150
Q
F
C
K
N
S
A
D
N
K
V
V
C
S
C
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
Y295
F
E
Y
C
D
L
N
Y
C
E
E
A
V
D
E
Dog
Lupus familis
XP_855946
493
54567
R182
T
T
V
G
R
R
K
R
A
T
E
T
A
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
Y287
G
Q
P
G
D
F
E
Y
C
N
L
N
Y
C
E
Rat
Rattus norvegicus
P18292
617
70393
Y286
A
Q
Q
P
G
F
E
Y
C
S
L
N
Y
C
D
Wallaby
Macropus eugenll
O18783
806
90963
P350
R
Q
E
Y
C
A
I
P
S
C
G
T
S
S
P
Platypus
Ornith. anatinus
XP_001511876
701
76014
A371
A
G
G
L
S
L
G
A
G
G
R
P
P
A
R
Chicken
Gallus gallus
P25155
475
53123
G164
G
Y
E
L
A
E
D
G
K
Q
C
V
S
K
V
Frog
Xenopus laevis
NP_001086517
607
69214
T275
F
V
S
H
P
N
L
T
Y
D
Y
C
P
M
N
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
R213
E
E
G
G
G
R
E
R
T
T
L
D
Q
R
K
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
Y284
S
G
K
V
I
V
D
Y
W
D
L
P
V
C
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
S633
T
D
Q
I
I
L
I
S
G
G
S
L
L
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
0
86.6
6.6
N.A.
26.6
13.3
0
13.3
0
6.6
0
26.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
93.3
6.6
N.A.
26.6
20
0
13.3
20
13.3
6.6
46.6
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
8
8
8
8
8
0
0
16
8
8
0
% A
% Cys:
0
0
8
16
8
0
0
0
31
8
8
8
8
24
8
% C
% Asp:
0
8
0
0
24
0
16
8
0
16
0
8
0
8
8
% D
% Glu:
8
16
16
0
0
8
24
0
0
16
24
0
0
8
31
% E
% Phe:
24
8
0
0
0
16
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
24
16
24
16
0
8
8
16
16
8
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
16
0
16
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
8
8
0
0
8
0
8
8
0
0
0
8
8
% K
% Leu:
0
0
0
16
0
31
8
0
0
0
31
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
8
16
0
8
8
0
16
0
0
8
% N
% Pro:
0
0
8
8
8
0
0
8
0
0
0
16
16
8
8
% P
% Gln:
8
24
16
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
8
0
0
0
8
16
0
16
0
0
8
0
0
8
16
% R
% Ser:
8
0
8
0
8
8
0
8
8
8
8
0
16
16
8
% S
% Thr:
16
8
0
0
0
0
0
8
8
16
0
16
0
0
0
% T
% Val:
0
8
8
8
0
8
0
0
0
0
8
16
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
16
8
0
0
0
39
8
0
8
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _