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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2 All Species: 30.61
Human Site: T502 Identified Species: 56.11
UniProt: P00734 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00734 NP_000497.1 622 70037 T502 A G Y K G R V T G W G N L K E
Chimpanzee Pan troglodytes Q95ND7 461 51746 G355 F G S G Y V S G W G R V F H K
Rhesus Macaque Macaca mulatta NP_001098055 627 70600 T507 A G Y K G R V T G W G N L K E
Dog Lupus familis XP_855946 493 54567 T387 H E K G R P S T T L K M M E V
Cat Felis silvestris
Mouse Mus musculus P19221 618 70250 T499 A G Y K G R V T G W G N L R E
Rat Rattus norvegicus P18292 617 70393 T498 A G Y K G R V T G W G N L R E
Wallaby Macropus eugenll O18783 806 90963 P641 G L H R E V N P E S Y S Q E I
Platypus Ornith. anatinus XP_001511876 701 76014 T583 S G Y K G R V T G W G N L K E
Chicken Gallus gallus P25155 475 53123 G369 Q K S G M V S G F G R E F E A
Frog Xenopus laevis NP_001086517 607 69214 T487 A G Y K G R V T G W G N L Q E
Zebra Danio Brachydanio rerio NP_998555 524 59542 P418 T S N P S N L P A V L Q Q I H
Tiger Blowfish Takifugu rubipres NP_001027864 612 69604 T496 T G F K G R V T G W G N L K E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783851 948 105521 T840 P D M M G R V T G W G Q I A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 92.6 32.9 N.A. 81.1 79.9 23.3 44.3 31.1 58.6 50.3 52.8 N.A. N.A. N.A. 24.4
Protein Similarity: 100 43.8 95 45.3 N.A. 88.7 88 37.1 54.2 46.7 74.4 64.4 70.7 N.A. N.A. N.A. 37.2
P-Site Identity: 100 6.6 100 6.6 N.A. 93.3 93.3 0 93.3 0 93.3 0 86.6 N.A. N.A. N.A. 53.3
P-Site Similarity: 100 13.3 100 20 N.A. 100 100 26.6 100 6.6 100 6.6 93.3 N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 0 0 0 0 0 0 8 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 8 0 0 0 8 0 0 8 0 24 62 % E
% Phe: 8 0 8 0 0 0 0 0 8 0 0 0 16 0 0 % F
% Gly: 8 62 0 24 62 0 0 16 62 16 62 0 0 0 0 % G
% His: 8 0 8 0 0 0 0 0 0 0 0 0 0 8 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 8 % I
% Lys: 0 8 8 54 0 0 0 0 0 0 8 0 0 31 8 % K
% Leu: 0 8 0 0 0 0 8 0 0 8 8 0 54 0 0 % L
% Met: 0 0 8 8 8 0 0 0 0 0 0 8 8 0 0 % M
% Asn: 0 0 8 0 0 8 8 0 0 0 0 54 0 0 0 % N
% Pro: 8 0 0 8 0 8 0 16 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 16 16 8 0 % Q
% Arg: 0 0 0 8 8 62 0 0 0 0 16 0 0 16 0 % R
% Ser: 8 8 16 0 8 0 24 0 0 8 0 8 0 0 0 % S
% Thr: 16 0 0 0 0 0 0 70 8 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 24 62 0 0 8 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 62 0 0 0 0 0 % W
% Tyr: 0 0 47 0 8 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _