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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
14.85
Human Site:
T196
Identified Species:
27.22
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
T196
D
Q
V
T
V
A
M
T
P
R
S
E
G
S
S
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
E63
V
Q
G
N
L
E
R
E
C
M
E
E
K
C
S
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
T204
D
Q
V
T
V
A
M
T
P
R
S
S
V
N
L
Dog
Lupus familis
XP_855946
493
54567
C95
D
Q
C
E
S
S
P
C
Q
N
Q
G
Q
C
K
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
T198
G
R
T
T
V
V
M
T
P
R
S
G
G
S
K
Rat
Rattus norvegicus
P18292
617
70393
T198
G
R
T
T
V
K
M
T
P
R
S
R
G
S
K
Wallaby
Macropus eugenll
O18783
806
90963
E191
E
C
M
H
C
S
G
E
N
Y
R
G
T
I
S
Platypus
Ornith. anatinus
XP_001511876
701
76014
Y283
L
P
E
E
G
R
L
Y
R
G
T
Q
A
T
T
Chicken
Gallus gallus
P25155
475
53123
T77
A
F
E
D
N
E
K
T
E
E
F
W
N
I
Y
Frog
Xenopus laevis
NP_001086517
607
69214
T186
C
V
I
T
V
C
G
T
N
K
T
T
V
E
P
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
S126
A
K
Y
A
G
K
V
S
V
T
K
S
G
K
A
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
F194
V
P
I
C
G
E
A
F
V
P
P
T
P
T
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
R296
N
N
V
V
L
G
K
R
D
F
T
R
P
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
20
73.3
13.3
N.A.
60
60
6.6
0
6.6
20
6.6
0
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
80
20
N.A.
66.6
66.6
26.6
33.3
6.6
40
33.3
13.3
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
8
0
16
8
0
0
0
0
0
8
0
16
% A
% Cys:
8
8
8
8
8
8
0
8
8
0
0
0
0
16
0
% C
% Asp:
24
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
0
16
16
0
24
0
16
8
8
8
16
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
8
8
0
0
0
0
% F
% Gly:
16
0
8
0
24
8
16
0
0
8
0
24
31
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
0
0
0
0
0
16
0
% I
% Lys:
0
8
0
0
0
16
16
0
0
8
8
0
8
8
24
% K
% Leu:
8
0
0
0
16
0
8
0
0
0
0
0
0
0
8
% L
% Met:
0
0
8
0
0
0
31
0
0
8
0
0
0
0
0
% M
% Asn:
8
8
0
8
8
0
0
0
16
8
0
0
8
16
0
% N
% Pro:
0
16
0
0
0
0
8
0
31
8
8
0
16
0
16
% P
% Gln:
0
31
0
0
0
0
0
0
8
0
8
8
8
0
0
% Q
% Arg:
0
16
0
0
0
8
8
8
8
31
8
16
0
0
0
% R
% Ser:
0
0
0
0
8
16
0
8
0
0
31
16
0
24
24
% S
% Thr:
0
0
16
39
0
0
0
47
0
8
24
16
8
16
8
% T
% Val:
16
8
24
8
39
8
8
0
16
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _