Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2 All Species: 9.7
Human Site: T171 Identified Species: 17.78
UniProt: P00734 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00734 NP_000497.1 622 70037 T171 T T G P W C Y T T D P T V R R
Chimpanzee Pan troglodytes Q95ND7 461 51746 N38 F L D H E N A N K I L N R P K
Rhesus Macaque Macaca mulatta NP_001098055 627 70600 T179 T T G P W C Y T T D P T V R R
Dog Lupus familis XP_855946 493 54567 V70 S F E E A R E V F E D T A K T
Cat Felis silvestris
Mouse Mus musculus P19221 618 70250 T173 T G P W C Y T T D P T V R R E
Rat Rattus norvegicus P18292 617 70393 T173 S G P W C Y T T D P T V R R E
Wallaby Macropus eugenll O18783 806 90963 T166 V K G P W C Y T T N P D I R Y
Platypus Ornith. anatinus XP_001511876 701 76014 P258 V S G R T E E P P T L R P R G
Chicken Gallus gallus P25155 475 53123 N52 L E E M K Q G N I E R E C N E
Frog Xenopus laevis NP_001086517 607 69214 N161 Y C R N P N D N P T G P W C Y
Zebra Danio Brachydanio rerio NP_998555 524 59542 N101 S R T P Q N I N S L R I C A T
Tiger Blowfish Takifugu rubipres NP_001027864 612 69604 D169 R N P N N S P D G P W C F T T
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783851 948 105521 W271 V I D Q S V Y W T D W M V K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 92.6 32.9 N.A. 81.1 79.9 23.3 44.3 31.1 58.6 50.3 52.8 N.A. N.A. N.A. 24.4
Protein Similarity: 100 43.8 95 45.3 N.A. 88.7 88 37.1 54.2 46.7 74.4 64.4 70.7 N.A. N.A. N.A. 37.2
P-Site Identity: 100 0 100 6.6 N.A. 20 13.3 60 13.3 0 0 6.6 0 N.A. N.A. N.A. 26.6
P-Site Similarity: 100 6.6 100 26.6 N.A. 20 20 73.3 20 6.6 0 20 0 N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 8 0 0 0 0 0 8 8 0 % A
% Cys: 0 8 0 0 16 24 0 0 0 0 0 8 16 8 0 % C
% Asp: 0 0 16 0 0 0 8 8 16 24 8 8 0 0 0 % D
% Glu: 0 8 16 8 8 8 16 0 0 16 0 8 0 0 24 % E
% Phe: 8 8 0 0 0 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 0 16 31 0 0 0 8 0 8 0 8 0 0 0 16 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 0 8 8 0 8 8 0 0 % I
% Lys: 0 8 0 0 8 0 0 0 8 0 0 0 0 16 8 % K
% Leu: 8 8 0 0 0 0 0 0 0 8 16 0 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 16 8 24 0 31 0 8 0 8 0 8 0 % N
% Pro: 0 0 24 31 8 0 8 8 16 24 24 8 8 8 0 % P
% Gln: 0 0 0 8 8 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 8 8 0 8 0 0 0 0 16 8 24 47 16 % R
% Ser: 24 8 0 0 8 8 0 0 8 0 0 0 0 0 0 % S
% Thr: 24 16 8 0 8 0 16 39 31 16 16 24 0 8 24 % T
% Val: 24 0 0 0 0 8 0 8 0 0 0 16 24 0 0 % V
% Trp: 0 0 0 16 24 0 0 8 0 0 16 0 8 0 0 % W
% Tyr: 8 0 0 0 0 16 31 0 0 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _