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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
23.33
Human Site:
S358
Identified Species:
42.78
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
S358
T
E
R
E
L
L
E
S
Y
I
D
G
R
I
V
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
T218
L
D
N
I
T
Q
S
T
Q
S
F
N
D
F
T
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
S363
T
E
G
E
L
L
E
S
Y
I
D
G
R
I
V
Dog
Lupus familis
XP_855946
493
54567
E250
G
Q
D
C
R
D
G
E
C
P
W
Q
A
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
S355
T
E
K
E
L
L
D
S
Y
I
D
G
R
I
V
Rat
Rattus norvegicus
P18292
617
70393
S354
T
E
K
E
L
L
D
S
Y
I
D
G
R
I
V
Wallaby
Macropus eugenll
O18783
806
90963
N418
P
N
A
D
L
I
R
N
Y
C
R
N
P
D
G
Platypus
Ornith. anatinus
XP_001511876
701
76014
G439
R
G
S
N
D
R
G
G
L
P
Y
L
L
G
Q
Chicken
Gallus gallus
P25155
475
53123
I232
P
P
R
N
G
S
S
I
T
D
P
N
V
D
T
Frog
Xenopus laevis
NP_001086517
607
69214
S343
S
E
K
E
L
L
E
S
Y
M
Q
G
R
I
V
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
Y281
A
P
W
Q
V
M
L
Y
K
R
S
P
Q
E
L
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
S352
S
E
D
E
L
L
Q
S
Y
R
E
K
R
I
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
G701
A
T
M
F
T
T
P
G
P
R
D
G
R
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
0
93.3
0
N.A.
86.6
86.6
13.3
0
6.6
73.3
0
60
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
13.3
93.3
20
N.A.
100
100
33.3
0
6.6
93.3
33.3
80
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% C
% Asp:
0
8
16
8
8
8
16
0
0
8
39
0
8
16
0
% D
% Glu:
0
47
0
47
0
0
24
8
0
0
8
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
8
8
8
0
8
0
16
16
0
0
0
47
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
8
0
31
0
0
0
47
0
% I
% Lys:
0
0
24
0
0
0
0
0
8
0
0
8
0
0
0
% K
% Leu:
8
0
0
0
54
47
8
0
8
0
0
8
8
8
16
% L
% Met:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
8
16
0
0
0
8
0
0
0
24
0
0
0
% N
% Pro:
16
16
0
0
0
0
8
0
8
16
8
8
8
0
0
% P
% Gln:
0
8
0
8
0
8
8
0
8
0
8
8
8
0
8
% Q
% Arg:
8
0
16
0
8
8
8
0
0
24
8
0
54
0
0
% R
% Ser:
16
0
8
0
0
8
16
47
0
8
8
0
0
0
0
% S
% Thr:
31
8
0
0
16
8
0
8
8
0
0
0
0
0
16
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
54
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
54
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _