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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2 All Species: 0.61
Human Site: S307 Identified Species: 1.11
UniProt: P00734 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00734 NP_000497.1 622 70037 S307 G D G L D E D S D R A I E G R
Chimpanzee Pan troglodytes Q95ND7 461 51746 Q167 G Y R L A E N Q K S C E P A V
Rhesus Macaque Macaca mulatta NP_001098055 627 70600 P312 G D G L G E D P D R A I E G R
Dog Lupus familis XP_855946 493 54567 E199 A P P D A E E E A G M L E Q Y
Cat Felis silvestris
Mouse Mus musculus P19221 618 70250 V304 V G E E N Y D V D E S I A G R
Rat Rattus norvegicus P18292 617 70393 G303 V G E E N H D G D E S I A G R
Wallaby Macropus eugenll O18783 806 90963 V367 D R V E Q S P V I Q E C Y E G
Platypus Ornith. anatinus XP_001511876 701 76014 L388 G P G R R R F L P D D P R V A
Chicken Gallus gallus P25155 475 53123 K181 P C G K V L M K R I K R S V I
Frog Xenopus laevis NP_001086517 607 69214 V292 D S P I D E D V L N N P A G R
Zebra Danio Brachydanio rerio NP_998555 524 59542 N230 F N P R S F G N G E L D C G E
Tiger Blowfish Takifugu rubipres NP_001027864 612 69604 D301 L S Q E E T L D T G A Q Q R T
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783851 948 105521 Y650 V R Q D S G K Y T C I V S D Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 92.6 32.9 N.A. 81.1 79.9 23.3 44.3 31.1 58.6 50.3 52.8 N.A. N.A. N.A. 24.4
Protein Similarity: 100 43.8 95 45.3 N.A. 88.7 88 37.1 54.2 46.7 74.4 64.4 70.7 N.A. N.A. N.A. 37.2
P-Site Identity: 100 20 86.6 13.3 N.A. 33.3 33.3 0 13.3 6.6 33.3 6.6 6.6 N.A. N.A. N.A. 0
P-Site Similarity: 100 26.6 86.6 26.6 N.A. 46.6 46.6 6.6 13.3 6.6 40 20 20 N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 16 0 0 0 8 0 24 0 24 8 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 8 8 8 8 0 0 % C
% Asp: 16 16 0 16 16 0 39 8 31 8 8 8 0 8 0 % D
% Glu: 0 0 16 31 8 39 8 8 0 24 8 8 24 8 8 % E
% Phe: 8 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % F
% Gly: 31 16 31 0 8 8 8 8 8 16 0 0 0 47 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 8 8 8 31 0 0 8 % I
% Lys: 0 0 0 8 0 0 8 8 8 0 8 0 0 0 0 % K
% Leu: 8 0 0 24 0 8 8 8 8 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 0 0 16 0 8 8 0 8 8 0 0 0 0 % N
% Pro: 8 16 24 0 0 0 8 8 8 0 0 16 8 0 0 % P
% Gln: 0 0 16 0 8 0 0 8 0 8 0 8 8 8 8 % Q
% Arg: 0 16 8 16 8 8 0 0 8 16 0 8 8 8 39 % R
% Ser: 0 16 0 0 16 8 0 8 0 8 16 0 16 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 16 0 0 0 0 0 8 % T
% Val: 24 0 8 0 8 0 0 24 0 0 0 8 0 16 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 0 8 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _