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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
8.18
Human Site:
S239
Identified Species:
15
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
S239
L
P
C
L
A
W
A
S
A
Q
A
K
A
L
S
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
G106
S
N
P
C
L
N
G
G
S
C
K
D
D
I
N
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
A247
L
A
W
A
S
A
Q
A
K
A
L
S
K
H
Q
Dog
Lupus familis
XP_855946
493
54567
Q138
V
D
N
G
D
C
D
Q
F
C
R
E
E
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
S241
S
P
C
L
P
W
N
S
L
P
A
K
T
L
S
Rat
Rattus norvegicus
P18292
617
70393
S241
S
P
C
L
A
W
D
S
L
P
T
K
T
L
S
Wallaby
Macropus eugenll
O18783
806
90963
C234
K
D
L
K
E
N
Y
C
R
N
P
D
G
E
P
Platypus
Ornith. anatinus
XP_001511876
701
76014
N326
L
V
E
N
H
C
R
N
P
D
G
D
S
E
G
Chicken
Gallus gallus
P25155
475
53123
N120
L
D
G
Y
Q
G
K
N
C
E
F
V
I
P
K
Frog
Xenopus laevis
NP_001086517
607
69214
L229
T
I
S
G
L
P
C
L
H
W
D
S
P
S
V
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
G169
N
P
D
K
H
K
D
G
P
W
C
F
T
R
D
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
S237
H
A
C
L
M
W
S
S
P
E
A
V
T
L
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
C339
P
T
A
I
G
R
S
C
A
C
A
D
G
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
0
6.6
6.6
N.A.
60
60
0
6.6
6.6
0
6.6
46.6
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
20
20
N.A.
60
60
0
20
20
0
6.6
60
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
8
16
8
8
8
16
8
31
0
8
0
0
% A
% Cys:
0
0
31
8
0
16
8
16
8
24
8
0
0
0
0
% C
% Asp:
0
24
8
0
8
0
24
0
0
8
8
31
8
0
16
% D
% Glu:
0
0
8
0
8
0
0
0
0
16
0
8
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% F
% Gly:
0
0
8
16
8
8
8
16
0
0
8
0
16
0
8
% G
% His:
8
0
0
0
16
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
8
0
0
16
0
8
8
0
8
0
8
24
8
0
8
% K
% Leu:
31
0
8
31
16
0
0
8
16
0
8
0
0
31
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
8
0
16
8
16
0
8
0
0
0
0
8
% N
% Pro:
8
31
8
0
8
8
0
0
24
16
8
0
8
8
8
% P
% Gln:
0
0
0
0
8
0
8
8
0
8
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
8
8
0
8
0
8
0
0
8
0
% R
% Ser:
24
0
8
0
8
0
16
31
8
0
0
16
8
8
39
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
8
0
31
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
16
0
8
8
% V
% Trp:
0
0
8
0
0
31
0
0
0
16
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _