KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOS
All Species:
21.21
Human Site:
T244
Identified Species:
38.89
UniProt:
P00540
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00540
NP_005363.1
346
37820
T244
Y
P
L
G
G
T
Y
T
H
R
A
P
E
L
L
Chimpanzee
Pan troglodytes
XP_528144
346
37828
T244
Y
P
L
G
G
T
Y
T
H
R
A
P
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001087400
305
33010
A206
G
G
T
Y
T
H
R
A
P
E
L
L
K
G
E
Dog
Lupus familis
XP_544088
372
41133
T270
Y
P
L
G
G
T
Y
T
H
R
A
P
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P00536
390
42872
T288
H
H
I
G
G
T
Y
T
H
Q
A
P
E
I
L
Rat
Rattus norvegicus
P00539
339
37603
H239
H
I
G
G
T
Y
T
H
Q
A
P
E
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P10741
349
38245
T248
C
Q
Q
G
G
T
Y
T
H
R
A
P
E
L
L
Frog
Xenopus laevis
P12965
359
39143
T238
R
H
V
G
G
T
Y
T
H
R
A
P
E
L
L
Zebra Danio
Brachydanio rerio
NP_991143
329
36509
F230
M
N
E
I
G
G
T
F
T
H
R
A
P
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1Y5
476
53320
N343
R
C
G
T
P
S
Y
N
A
P
E
I
V
A
N
Sea Urchin
Strong. purpuratus
XP_789415
418
47752
T311
P
T
N
R
S
Y
L
T
G
T
C
G
Y
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130627
368
40934
P234
G
T
Y
R
W
M
A
P
E
M
I
K
E
E
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2MHE4
390
44263
P255
G
T
Y
R
W
M
A
P
E
M
I
K
E
K
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.5
78.4
N.A.
65.3
71
N.A.
N.A.
62.1
53.7
46.5
N.A.
N.A.
N.A.
20.1
26.3
Protein Similarity:
100
99.4
86.4
83.5
N.A.
71.7
78.9
N.A.
N.A.
72.7
66.5
62.1
N.A.
N.A.
N.A.
36.1
40.6
P-Site Identity:
100
100
0
100
N.A.
66.6
13.3
N.A.
N.A.
80
80
13.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
93.3
20
N.A.
N.A.
80
86.6
13.3
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
29.6
N.A.
22.8
N.A.
N.A.
Protein Similarity:
N.A.
43.2
N.A.
42
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
8
8
8
47
8
0
8
8
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
16
8
8
8
62
16
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
24
8
16
54
54
8
0
0
8
0
0
8
0
8
0
% G
% His:
16
16
0
0
0
8
0
8
47
8
0
0
0
0
8
% H
% Ile:
0
8
8
8
0
0
0
0
0
0
16
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
16
8
8
8
% K
% Leu:
0
0
24
0
0
0
8
0
0
0
8
8
8
47
54
% L
% Met:
8
0
0
0
0
16
0
0
0
16
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
8
24
0
0
8
0
0
16
8
8
8
47
8
0
8
% P
% Gln:
0
8
8
0
0
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
16
0
0
24
0
0
8
0
0
39
8
0
0
8
0
% R
% Ser:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
24
8
8
16
47
16
54
8
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
0
16
8
0
16
54
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _