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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OTC
All Species:
29.09
Human Site:
Y284
Identified Species:
58.18
UniProt:
P00480
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00480
NP_000522.3
354
39935
Y284
R
L
Q
A
F
Q
G
Y
Q
V
T
M
K
T
A
Chimpanzee
Pan troglodytes
XP_001139972
223
25139
M157
F
Q
G
Y
Q
V
T
M
K
T
A
K
V
A
A
Rhesus Macaque
Macaca mulatta
XP_001086929
254
28283
M188
F
Q
G
Y
Q
V
T
M
K
T
A
K
V
A
A
Dog
Lupus familis
XP_537995
354
39887
Y284
R
L
Q
A
F
Q
G
Y
Q
V
T
M
K
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P11725
354
39746
Y284
R
L
Q
A
F
Q
G
Y
Q
V
T
M
K
T
A
Rat
Rattus norvegicus
P00481
354
39868
Y284
R
L
Q
A
F
Q
G
Y
Q
V
T
M
K
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513452
362
40782
Y292
R
L
R
D
F
Q
G
Y
Q
I
T
M
K
T
G
Chicken
Gallus gallus
Q9YHY9
354
40227
Y284
R
L
K
A
F
Q
G
Y
Q
I
T
M
Q
T
V
Frog
Xenopus laevis
NP_001079087
351
39217
Y281
R
L
K
D
F
N
G
Y
Q
I
T
M
Q
T
G
Zebra Danio
Brachydanio rerio
XP_001334671
352
39645
Y282
R
L
K
D
F
S
G
Y
Q
I
T
I
Q
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793635
357
39695
A271
P
M
E
A
C
Q
G
A
N
V
I
V
T
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P05150
338
37827
F270
K
L
K
Q
F
K
G
F
Q
I
N
Q
E
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.3
71.1
96.8
N.A.
92.6
91.8
N.A.
82.3
75.4
75.1
68.3
N.A.
N.A.
N.A.
N.A.
56.3
Protein Similarity:
100
57
71.1
97.4
N.A.
96
95.1
N.A.
88.6
85.8
85.3
80.2
N.A.
N.A.
N.A.
N.A.
70.3
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
73.3
73.3
60
53.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
86.6
93.3
80
80
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
0
9
0
0
17
0
0
17
50
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
25
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
17
0
0
0
75
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
84
0
0
0
0
0
0
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
42
9
9
0
0
0
% I
% Lys:
9
0
34
0
0
9
0
0
17
0
0
17
42
0
0
% K
% Leu:
0
75
0
0
0
0
0
0
0
0
0
0
0
9
0
% L
% Met:
0
9
0
0
0
0
0
17
0
0
0
59
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
9
0
9
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
34
9
17
59
0
0
75
0
0
9
25
0
0
% Q
% Arg:
67
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
17
0
0
17
67
0
9
67
9
% T
% Val:
0
0
0
0
0
17
0
0
0
42
0
9
17
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _