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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSR
All Species:
21.21
Human Site:
Y371
Identified Species:
35.9
UniProt:
P00390
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00390
NP_000628.2
522
56257
Y371
N
T
N
V
K
G
I
Y
A
V
G
D
V
C
G
Chimpanzee
Pan troglodytes
XP_519696
522
56320
Y371
N
T
N
V
K
G
I
Y
A
V
G
D
V
C
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532813
521
56117
Y370
N
T
S
V
K
G
I
Y
A
V
G
D
V
C
G
Cat
Felis silvestris
Mouse
Mus musculus
P47791
500
53644
Y349
N
T
N
V
K
G
V
Y
A
V
G
D
V
C
G
Rat
Rattus norvegicus
P70619
424
46283
G302
L
A
H
R
L
F
E
G
K
E
D
S
R
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518656
568
62147
Y417
N
T
N
R
R
G
V
Y
A
V
G
D
V
C
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089322
476
51712
E353
K
L
S
H
R
L
F
E
G
Q
E
D
S
K
L
Zebra Danio
Brachydanio rerio
NP_001018390
425
46052
H303
V
K
L
D
E
R
G
H
I
V
V
D
E
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
V429
N
V
A
N
I
Y
A
V
G
D
I
I
Y
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30635
503
55027
N363
L
A
D
R
L
F
S
N
S
K
Q
I
V
R
F
Sea Urchin
Strong. purpuratus
XP_794131
1196
132606
Y1045
N
T
T
T
P
N
I
Y
A
L
G
D
V
C
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
W392
Q
T
S
V
P
S
I
W
A
V
G
D
V
T
D
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
K351
V
A
I
A
A
G
R
K
L
S
N
R
L
F
G
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
R346
L
F
G
P
E
E
F
R
T
L
K
L
N
Y
D
Conservation
Percent
Protein Identity:
100
99
N.A.
86.4
N.A.
83.3
70.1
N.A.
67.2
N.A.
69.7
55.3
N.A.
32.3
N.A.
34
24.1
Protein Similarity:
100
99.2
N.A.
91.9
N.A.
89.4
75.6
N.A.
76.7
N.A.
80.4
68.1
N.A.
47.6
N.A.
52.1
32.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
0
N.A.
80
N.A.
6.6
13.3
N.A.
6.6
N.A.
6.6
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
93.3
N.A.
20
26.6
N.A.
6.6
N.A.
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
47.5
47.3
Protein Similarity:
N.A.
N.A.
N.A.
52.2
62.4
62.8
P-Site Identity:
N.A.
N.A.
N.A.
53.3
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
8
8
8
0
8
0
50
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
8
8
65
0
0
22
% D
% Glu:
0
0
0
0
15
8
8
8
0
8
8
0
8
0
0
% E
% Phe:
0
8
0
0
0
15
15
0
0
0
0
0
0
15
8
% F
% Gly:
0
0
8
0
0
43
8
8
15
0
50
0
0
8
50
% G
% His:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
36
0
8
0
8
15
0
0
0
% I
% Lys:
8
8
0
0
29
0
0
8
8
8
8
0
0
8
8
% K
% Leu:
22
8
8
0
15
8
0
0
8
15
0
8
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
29
8
0
8
0
8
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
8
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% Q
% Arg:
0
0
0
22
15
8
8
8
0
0
0
8
8
8
0
% R
% Ser:
0
0
22
0
0
8
8
0
8
8
0
8
8
0
0
% S
% Thr:
0
50
8
8
0
0
0
0
8
0
0
0
0
8
0
% T
% Val:
15
8
0
36
0
0
15
8
0
50
8
0
58
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
43
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _