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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GSR All Species: 9.09
Human Site: S210 Identified Species: 15.38
UniProt: P00390 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00390 NP_000628.2 522 56257 S210 M P S T P H E S Q I P G A S L
Chimpanzee Pan troglodytes XP_519696 522 56320 S210 M P S T P H E S Q I P G A R L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532813 521 56117 S209 V P S R P Q E S Q I P G A S L
Cat Felis silvestris
Mouse Mus musculus P47791 500 53644 P191 V P H E S Q I P G A S L G I T
Rat Rattus norvegicus P70619 424 46283 I144 A G Y I A V E I A G I L S A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518656 568 62147 Q256 L P S L P S E Q Q I P G A S L
Chicken Gallus gallus
Frog Xenopus laevis NP_001089322 476 51712 A193 R R S I V V G A G Y I A V E I
Zebra Danio Brachydanio rerio NP_001018390 425 46052 G145 T H I L I S T G G H P S T V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91938 596 64304 D271 G G R P R Y P D I P G A V E Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30635 503 55027 L205 A S V P G K T L I V G G G Y V
Sea Urchin Strong. purpuratus XP_794131 1196 132606 S624 S S L Q P H G S T G L Q V L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42770 565 60834 A231 T T R N I L I A V G G R P F I
Baker's Yeast Sacchar. cerevisiae P41921 483 53422 R192 T D S D G F F R L E E Q P K K
Red Bread Mold Neurospora crassa Q873E8 468 50294 I188 A L V G A G Y I A V E F A G M
Conservation
Percent
Protein Identity: 100 99 N.A. 86.4 N.A. 83.3 70.1 N.A. 67.2 N.A. 69.7 55.3 N.A. 32.3 N.A. 34 24.1
Protein Similarity: 100 99.2 N.A. 91.9 N.A. 89.4 75.6 N.A. 76.7 N.A. 80.4 68.1 N.A. 47.6 N.A. 52.1 32.6
P-Site Identity: 100 93.3 N.A. 80 N.A. 6.6 13.3 N.A. 73.3 N.A. 6.6 6.6 N.A. 0 N.A. 6.6 20
P-Site Similarity: 100 93.3 N.A. 86.6 N.A. 13.3 26.6 N.A. 80 N.A. 20 6.6 N.A. 6.6 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. 37.1 47.5 47.3
Protein Similarity: N.A. N.A. N.A. 52.2 62.4 62.8
P-Site Identity: N.A. N.A. N.A. 0 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 0 15 0 0 15 15 8 0 15 36 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 36 0 0 8 15 0 0 15 0 % E
% Phe: 0 0 0 0 0 8 8 0 0 0 0 8 0 8 0 % F
% Gly: 8 15 0 8 15 8 15 8 22 22 22 36 15 8 0 % G
% His: 0 8 8 0 0 22 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 8 15 15 0 15 15 15 29 15 0 0 8 15 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 8 % K
% Leu: 8 8 8 15 0 8 0 8 8 0 8 15 0 8 36 % L
% Met: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 36 0 15 36 0 8 8 0 8 36 0 15 0 0 % P
% Gln: 0 0 0 8 0 15 0 8 29 0 0 15 0 0 0 % Q
% Arg: 8 8 15 8 8 0 0 8 0 0 0 8 0 8 0 % R
% Ser: 8 15 43 0 8 15 0 29 0 0 8 8 8 22 15 % S
% Thr: 22 8 0 15 0 0 15 0 8 0 0 0 8 0 8 % T
% Val: 15 0 15 0 8 15 0 0 8 15 0 0 22 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 8 8 0 0 8 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _