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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GSR All Species: 14.24
Human Site: S205 Identified Species: 24.1
UniProt: P00390 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00390 NP_000628.2 522 56257 S205 I A T G G M P S T P H E S Q I
Chimpanzee Pan troglodytes XP_519696 522 56320 S205 I A T G G M P S T P H E S Q I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532813 521 56117 S204 I A T G G V P S R P Q E S Q I
Cat Felis silvestris
Mouse Mus musculus P47791 500 53644 H186 G G V P T V P H E S Q I P G A
Rat Rattus norvegicus P70619 424 46283 Y139 S V I V G A G Y I A V E I A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518656 568 62147 S251 I A T G G L P S L P S E Q Q I
Chicken Gallus gallus
Frog Xenopus laevis NP_001089322 476 51712 S188 L T D L P R R S I V V G A G Y
Zebra Danio Brachydanio rerio NP_001018390 425 46052 I140 K K Y T A T H I L I S T G G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91938 596 64304 R266 F V I A V G G R P R Y P D I P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30635 503 55027 V200 D L F T L A S V P G K T L I V
Sea Urchin Strong. purpuratus XP_794131 1196 132606 L619 G R S V K S S L Q P H G S T G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42770 565 60834 R226 D G K I Y T T R N I L I A V G
Baker's Yeast Sacchar. cerevisiae P41921 483 53422 S187 G F E L G T D S D G F F R L E
Red Bread Mold Neurospora crassa Q873E8 468 50294 V183 L P K K V A L V G A G Y I A V
Conservation
Percent
Protein Identity: 100 99 N.A. 86.4 N.A. 83.3 70.1 N.A. 67.2 N.A. 69.7 55.3 N.A. 32.3 N.A. 34 24.1
Protein Similarity: 100 99.2 N.A. 91.9 N.A. 89.4 75.6 N.A. 76.7 N.A. 80.4 68.1 N.A. 47.6 N.A. 52.1 32.6
P-Site Identity: 100 100 N.A. 80 N.A. 6.6 13.3 N.A. 73.3 N.A. 6.6 0 N.A. 0 N.A. 0 20
P-Site Similarity: 100 100 N.A. 86.6 N.A. 13.3 13.3 N.A. 80 N.A. 20 0 N.A. 6.6 N.A. 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 37.1 47.5 47.3
Protein Similarity: N.A. N.A. N.A. 52.2 62.4 62.8
P-Site Identity: N.A. N.A. N.A. 0 13.3 0
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 0 8 8 22 0 0 0 15 0 0 15 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 8 0 0 0 8 0 8 0 0 0 8 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 8 0 0 36 0 0 8 % E
% Phe: 8 8 8 0 0 0 0 0 0 0 8 8 0 0 0 % F
% Gly: 22 15 0 29 43 8 15 0 8 15 8 15 8 22 22 % G
% His: 0 0 0 0 0 0 8 8 0 0 22 0 0 0 8 % H
% Ile: 29 0 15 8 0 0 0 8 15 15 0 15 15 15 29 % I
% Lys: 8 8 15 8 8 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 15 8 0 15 8 8 8 8 15 0 8 0 8 8 0 % L
% Met: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 8 0 8 8 0 36 0 15 36 0 8 8 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 15 0 8 29 0 % Q
% Arg: 0 8 0 0 0 8 8 15 8 8 0 0 8 0 0 % R
% Ser: 8 0 8 0 0 8 15 43 0 8 15 0 29 0 0 % S
% Thr: 0 8 29 15 8 22 8 0 15 0 0 15 0 8 0 % T
% Val: 0 15 8 15 15 15 0 15 0 8 15 0 0 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 8 0 0 8 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _