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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYB5A
All Species:
36.36
Human Site:
Y35
Identified Species:
61.54
UniProt:
P00167
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00167
NP_001905.1
134
15330
Y35
L
I
L
H
H
K
V
Y
D
L
T
K
F
L
E
Chimpanzee
Pan troglodytes
XP_001135885
134
15297
Y35
L
I
L
H
H
K
V
Y
D
L
T
K
F
L
E
Rhesus Macaque
Macaca mulatta
XP_001083378
134
15287
Y35
L
I
L
H
H
K
V
Y
D
L
T
K
F
L
E
Dog
Lupus familis
XP_533373
134
15326
Y35
L
I
L
H
H
K
V
Y
D
L
T
K
F
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P56395
134
15222
Y35
V
I
L
H
H
K
V
Y
D
L
T
K
F
L
E
Rat
Rattus norvegicus
P00173
134
15337
Y35
V
I
L
H
H
K
V
Y
D
L
T
K
F
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P00174
138
15527
Y40
I
I
V
H
H
R
I
Y
D
I
T
K
F
L
D
Frog
Xenopus laevis
NP_001086707
132
15225
V35
L
H
N
K
V
Y
D
V
T
K
F
L
E
E
H
Zebra Danio
Brachydanio rerio
NP_998300
137
15360
Y37
I
I
I
H
N
K
V
Y
D
V
T
K
F
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4N3
134
15187
A36
N
N
I
Y
D
V
T
A
F
L
N
E
H
P
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794053
142
15655
Y41
L
V
I
H
N
K
V
Y
D
V
T
Q
F
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48845
134
14997
K35
G
K
V
Y
N
V
T
K
F
L
E
D
H
P
G
Baker's Yeast
Sacchar. cerevisiae
P40312
120
13278
K34
V
Y
D
V
S
Q
F
K
D
E
H
P
G
G
D
Red Bread Mold
Neurospora crassa
Q9P5L0
139
14595
D35
Y
D
I
T
K
F
V
D
E
H
P
G
G
E
E
Conservation
Percent
Protein Identity:
100
99.2
97.7
90.3
N.A.
87.3
88
N.A.
N.A.
73.9
76.8
66.4
N.A.
47
N.A.
N.A.
47.8
Protein Similarity:
100
99.2
100
94.7
N.A.
94.7
94.7
N.A.
N.A.
87.6
86.5
84.6
N.A.
64.1
N.A.
N.A.
69
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
60
6.6
73.3
N.A.
6.6
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
6.6
100
N.A.
26.6
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.8
29.1
36.6
Protein Similarity:
N.A.
N.A.
N.A.
61.9
55.9
54.6
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
0
8
8
72
0
0
8
0
0
22
% D
% Glu:
0
0
0
0
0
0
0
0
8
8
8
8
8
15
58
% E
% Phe:
0
0
0
0
0
8
8
0
15
0
8
0
65
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
8
15
8
15
% G
% His:
0
8
0
65
50
0
0
0
0
8
8
0
15
0
8
% H
% Ile:
15
58
29
0
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
8
8
58
0
15
0
8
0
58
0
0
0
% K
% Leu:
43
0
43
0
0
0
0
0
0
58
0
8
0
65
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
0
22
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
8
0
15
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
15
0
8
0
65
0
0
0
0
% T
% Val:
22
8
15
8
8
15
65
8
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
15
0
8
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _