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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5A All Species: 40.3
Human Site: T70 Identified Species: 68.21
UniProt: P00167 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00167 NP_001905.1 134 15330 T70 F E D V G H S T D A R E M S K
Chimpanzee Pan troglodytes XP_001135885 134 15297 T70 F E D V G H S T D A R E M S K
Rhesus Macaque Macaca mulatta XP_001083378 134 15287 T70 F E D V G H S T D A R E M S K
Dog Lupus familis XP_533373 134 15326 T70 F E D V G H S T D A R E L S K
Cat Felis silvestris
Mouse Mus musculus P56395 134 15222 T70 F E D V G H S T D A R E L S K
Rat Rattus norvegicus P00173 134 15337 T70 F E D V G H S T D A R E L S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P00174 138 15527 T75 F E D V G H S T D A R A L S E
Frog Xenopus laevis NP_001086707 132 15225 T68 F E D I G H S T D A R N M S K
Zebra Danio Brachydanio rerio NP_998300 137 15360 T72 F E D V G H S T D A R E M A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4N3 134 15187 N67 F E D V G H S N D A R D M M K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794053 142 15655 S76 F E D V G H S S D A R E L M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O48845 134 14997 E66 F E D V G H S E S A R E M M E
Baker's Yeast Sacchar. cerevisiae P40312 120 13278 S62 S F V D I G H S D E A L R L L
Red Bread Mold Neurospora crassa Q9P5L0 139 14595 D63 F E D V G H S D E A R E A L E
Conservation
Percent
Protein Identity: 100 99.2 97.7 90.3 N.A. 87.3 88 N.A. N.A. 73.9 76.8 66.4 N.A. 47 N.A. N.A. 47.8
Protein Similarity: 100 99.2 100 94.7 N.A. 94.7 94.7 N.A. N.A. 87.6 86.5 84.6 N.A. 64.1 N.A. N.A. 69
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 80 86.6 86.6 N.A. 80 N.A. N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 93.3 93.3 N.A. 86.6 N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 38.8 29.1 36.6
Protein Similarity: N.A. N.A. N.A. 61.9 55.9 54.6
P-Site Identity: N.A. N.A. N.A. 73.3 6.6 66.6
P-Site Similarity: N.A. N.A. N.A. 80 13.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 93 8 8 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 93 8 0 0 0 8 86 0 0 8 0 0 0 % D
% Glu: 0 93 0 0 0 0 0 8 8 8 0 72 0 0 22 % E
% Phe: 93 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 93 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 93 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 8 36 15 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 50 22 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 93 0 8 0 0 % R
% Ser: 8 0 0 0 0 0 93 15 8 0 0 0 0 58 8 % S
% Thr: 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 % T
% Val: 0 0 8 86 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _