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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAND1
All Species:
25.45
Human Site:
S48
Identified Species:
50.91
UniProt:
O96004
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96004
NP_004812.1
215
23627
S48
Y
F
Q
S
W
L
L
S
P
A
D
A
A
P
D
Chimpanzee
Pan troglodytes
XP_518050
215
23636
S48
Y
F
Q
S
W
L
L
S
P
A
D
A
A
P
D
Rhesus Macaque
Macaca mulatta
XP_001111722
215
23522
S48
Y
F
Q
S
W
L
L
S
P
A
D
A
A
P
D
Dog
Lupus familis
XP_546282
331
35691
S164
Y
F
Q
S
W
L
L
S
P
A
D
A
A
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q64279
216
23787
S48
Y
F
Q
S
W
L
L
S
P
A
D
A
A
P
D
Rat
Rattus norvegicus
P97832
216
23791
S48
Y
F
Q
S
W
L
L
S
P
A
D
A
A
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508110
232
25238
N67
Y
F
Q
S
W
V
L
N
P
G
D
A
S
A
D
Chicken
Gallus gallus
Q90691
202
22660
N45
Y
F
P
G
W
V
L
N
P
A
E
V
T
P
E
Frog
Xenopus laevis
O73615
197
21983
N40
Y
F
Q
G
W
V
L
N
P
G
E
V
S
P
E
Zebra Danio
Brachydanio rerio
P57102
208
23149
S42
Y
F
H
G
W
L
I
S
H
P
E
M
S
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609370
174
20059
Q37
K
H
S
E
S
Q
V
Q
Q
Q
I
Y
N
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20561
147
16728
P12
S
S
G
C
G
G
L
P
V
S
Q
C
P
S
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.5
63.1
N.A.
92.1
93.5
N.A.
71.9
71.6
66
50.2
N.A.
33.4
N.A.
22.7
N.A.
Protein Similarity:
100
99.5
99
63.7
N.A.
93
93.9
N.A.
77.5
78.1
75.8
62.7
N.A.
45.5
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
66.6
46.6
46.6
40
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
73.3
80
60
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
59
0
59
50
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
59
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
25
0
0
0
17
% E
% Phe:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
25
9
9
0
0
0
17
0
0
0
0
0
% G
% His:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
59
84
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
0
0
0
0
9
0
0
% N
% Pro:
0
0
9
0
0
0
0
9
75
9
0
0
9
75
9
% P
% Gln:
0
0
67
0
0
9
0
9
9
9
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
9
59
9
0
0
59
0
9
0
0
25
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% T
% Val:
0
0
0
0
0
25
9
0
9
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
84
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
84
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _