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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL18BP All Species: 7.58
Human Site: S189 Identified Species: 41.67
UniProt: O95998 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95998 NP_001034748.1 194 21099 S189 A L P S S H S S P Q Q Q G _ _
Chimpanzee Pan troglodytes XP_001174584 194 21080 S189 A L P S S H S S P Q Q Q G _ _
Rhesus Macaque Macaca mulatta NP_001116825 207 22401 T186 A L P S S H S T G P Q Q P T A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9Z0M9 193 21239 V184 T L S S H S P V S R S A G P G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519262 160 17738
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 83.5 N.A. N.A. 62.3 N.A. N.A. 26.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 88.4 N.A. N.A. 69 N.A. N.A. 37.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 60 N.A. N.A. 20 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 66.6 N.A. N.A. 33.3 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 0 0 0 0 0 0 0 0 0 0 20 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 20 0 0 0 60 0 20 % G
% His: 0 0 0 0 20 60 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 60 0 0 0 20 0 40 20 0 0 20 20 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 40 60 60 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % R
% Ser: 0 0 20 80 60 20 60 40 20 0 20 0 0 0 0 % S
% Thr: 20 0 0 0 0 0 0 20 0 0 0 0 0 20 0 % T
% Val: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 40 40 % _