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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
4.55
Human Site:
Y1374
Identified Species:
9.09
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
Y1374
R
A
L
P
V
P
V
Y
M
L
V
P
A
P
A
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
Q1588
L
P
S
Q
N
R
L
Q
P
Q
K
H
V
S
F
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
Y1376
R
A
L
P
V
P
V
Y
M
L
V
P
A
P
A
Dog
Lupus familis
XP_542202
2539
269675
R1626
A
A
V
P
A
R
L
R
K
V
A
S
A
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
P1350
K
V
A
S
A
L
V
P
G
R
R
S
L
P
V
Rat
Rattus norvegicus
P70478
2842
310514
Q1623
L
P
S
Q
S
R
L
Q
A
Q
K
H
V
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
Q1630
L
P
S
Q
S
R
L
Q
P
Q
K
H
V
S
F
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
Q1627
L
S
S
Q
N
R
L
Q
T
Q
K
H
V
N
F
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
I1215
L
L
V
T
D
Q
K
I
S
S
S
D
P
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
P1343
I
A
A
G
C
N
R
P
K
S
N
L
G
F
S
Honey Bee
Apis mellifera
XP_624558
2760
306907
G1712
R
K
K
S
L
P
L
G
V
V
A
K
R
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
R1667
R
L
P
S
A
D
V
R
H
K
S
P
S
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
0
100
20
N.A.
13.3
0
N.A.
0
N.A.
0
0
N.A.
6.6
13.3
N.A.
26.6
P-Site Similarity:
100
6.6
100
40
N.A.
20
6.6
N.A.
6.6
N.A.
13.3
6.6
N.A.
13.3
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
34
17
0
25
0
0
0
9
0
17
0
25
9
17
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
34
% F
% Gly:
0
0
0
9
0
0
0
9
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
34
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
9
0
0
0
0
0
9
9
% I
% Lys:
9
9
9
0
0
0
9
0
17
9
34
9
0
0
0
% K
% Leu:
42
17
17
0
9
9
50
0
0
17
0
9
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
9
0
0
0
0
9
0
0
9
0
% N
% Pro:
0
25
9
25
0
25
0
17
17
0
0
25
9
34
0
% P
% Gln:
0
0
0
34
0
9
0
34
0
34
0
0
0
0
0
% Q
% Arg:
34
0
0
0
0
42
9
17
0
9
9
0
9
0
0
% R
% Ser:
0
9
34
25
17
0
0
0
9
17
17
17
9
25
9
% S
% Thr:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
9
17
0
17
0
34
0
9
17
17
0
34
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _