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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
11.21
Human Site:
T2173
Identified Species:
22.42
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
T2173
A
L
P
L
R
G
S
T
P
E
D
A
P
A
G
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
E2603
S
G
A
T
N
G
A
E
S
K
T
L
I
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
T2173
A
L
P
L
R
G
S
T
P
E
D
A
P
A
G
Dog
Lupus familis
XP_542202
2539
269675
P2410
A
L
P
L
M
G
A
P
P
E
E
G
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
S2143
A
L
P
L
R
V
S
S
P
E
D
S
P
A
G
Rat
Rattus norvegicus
P70478
2842
310514
N2624
E
S
E
I
S
P
T
N
T
V
S
Q
T
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
G2625
E
S
E
M
A
P
A
G
N
T
P
Q
A
V
S
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
S2618
S
E
I
L
E
T
P
S
N
G
S
S
S
T
I
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
P1965
S
T
P
P
A
R
I
P
K
S
S
S
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
R2227
P
A
P
A
R
L
E
R
Q
G
T
F
V
K
D
Honey Bee
Apis mellifera
XP_624558
2760
306907
K2595
I
M
G
V
Q
P
S
K
V
K
Y
R
N
S
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
T2756
G
G
K
I
V
S
P
T
R
E
T
A
E
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
6.6
100
60
N.A.
80
0
N.A.
0
N.A.
6.6
6.6
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
26.6
100
73.3
N.A.
93.3
13.3
N.A.
13.3
N.A.
26.6
20
N.A.
13.3
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
9
9
17
0
25
0
0
0
0
25
9
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
17
% D
% Glu:
17
9
17
0
9
0
9
9
0
42
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
9
17
9
0
0
34
0
9
0
17
0
9
0
25
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
17
0
0
9
0
0
0
0
0
9
0
9
% I
% Lys:
0
0
9
0
0
0
0
9
9
17
0
0
0
9
0
% K
% Leu:
0
34
0
42
0
9
0
0
0
0
0
9
0
0
0
% L
% Met:
0
9
0
9
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
17
0
0
0
9
0
0
% N
% Pro:
9
0
50
9
0
25
17
17
34
0
9
0
34
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
0
0
17
0
0
9
% Q
% Arg:
0
0
0
0
34
9
0
9
9
0
0
9
0
0
0
% R
% Ser:
25
17
0
0
9
9
34
17
9
9
25
25
17
9
25
% S
% Thr:
0
9
0
9
0
9
9
25
9
9
25
0
9
17
0
% T
% Val:
0
0
0
9
9
9
0
0
9
9
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _