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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
33.64
Human Site:
S548
Identified Species:
67.27
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S548
V
L
R
A
T
K
E
S
T
L
K
S
V
L
S
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
S546
A
L
E
V
K
K
E
S
T
L
K
S
V
L
S
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
S550
V
L
R
A
T
K
E
S
T
L
K
S
V
L
S
Dog
Lupus familis
XP_542202
2539
269675
S836
V
L
R
A
S
K
E
S
T
L
K
S
V
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
S541
V
L
R
A
S
K
E
S
T
L
K
S
V
L
S
Rat
Rattus norvegicus
P70478
2842
310514
S581
A
L
E
V
K
K
E
S
T
L
K
S
V
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S583
A
L
E
V
K
K
E
S
T
L
K
S
V
L
S
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
S585
A
L
D
V
K
K
E
S
T
L
K
S
V
L
S
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
H483
D
Q
E
L
Y
G
M
H
N
E
P
I
N
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
K522
L
S
Y
E
G
P
S
K
T
L
K
I
I
E
N
Honey Bee
Apis mellifera
XP_624558
2760
306907
S561
A
M
E
G
R
K
E
S
T
L
K
S
I
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
S556
S
L
E
V
K
K
E
S
T
L
K
S
V
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
73.3
100
93.3
N.A.
93.3
73.3
N.A.
73.3
N.A.
73.3
0
N.A.
20
60
N.A.
73.3
P-Site Similarity:
100
73.3
100
100
N.A.
100
73.3
N.A.
73.3
N.A.
73.3
13.3
N.A.
40
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
0
34
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
50
9
0
0
84
0
0
9
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
17
17
0
0
% I
% Lys:
0
0
0
0
42
84
0
9
0
0
92
0
0
0
0
% K
% Leu:
9
75
0
9
0
0
0
0
0
92
0
0
0
84
0
% L
% Met:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
34
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
0
17
0
9
84
0
0
0
84
0
0
84
% S
% Thr:
0
0
0
0
17
0
0
0
92
0
0
0
0
0
0
% T
% Val:
34
0
0
42
0
0
0
0
0
0
0
0
75
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _