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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
14.85
Human Site:
S2259
Identified Species:
29.7
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S2259
A
V
G
G
F
P
A
S
R
H
G
S
P
S
R
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
H2734
S
S
S
S
S
S
K
H
S
S
P
S
G
T
V
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
S2259
A
V
G
G
F
P
A
S
R
H
G
S
P
S
R
Dog
Lupus familis
XP_542202
2539
269675
S2496
A
A
G
G
F
P
A
S
R
H
G
S
P
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
S2229
V
I
A
G
F
P
T
S
R
H
G
S
P
S
R
Rat
Rattus norvegicus
P70478
2842
310514
H2769
S
S
S
S
S
S
K
H
S
S
P
S
G
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
H2771
S
S
S
S
S
S
K
H
S
S
P
S
G
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
N2780
N
P
S
P
R
K
S
N
G
E
N
S
T
S
R
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
S2048
S
R
Q
T
R
N
I
S
P
L
V
T
N
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
S2311
A
G
K
S
H
A
A
S
R
V
V
S
G
R
V
Honey Bee
Apis mellifera
XP_624558
2760
306907
G2683
S
A
Q
T
Y
V
S
G
A
G
M
R
T
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
P3166
V
V
P
V
L
V
S
P
Y
N
Y
S
P
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
6.6
100
93.3
N.A.
73.3
6.6
N.A.
6.6
N.A.
20
6.6
N.A.
33.3
0
N.A.
20
P-Site Similarity:
100
20
100
93.3
N.A.
80
20
N.A.
20
N.A.
33.3
20
N.A.
33.3
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
17
9
0
0
9
34
0
9
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
25
34
0
0
0
9
9
9
34
0
34
0
0
% G
% His:
0
0
0
0
9
0
0
25
0
34
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
9
25
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
9
0
9
9
0
9
9
0
% N
% Pro:
0
9
9
9
0
34
0
9
9
0
25
0
42
9
17
% P
% Gln:
0
0
17
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
9
0
0
17
0
0
0
42
0
0
9
0
9
42
% R
% Ser:
42
25
34
34
25
25
25
50
25
25
0
84
0
42
0
% S
% Thr:
0
0
0
17
0
0
9
0
0
0
0
9
17
17
0
% T
% Val:
17
25
0
9
0
17
0
0
0
9
17
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _