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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
14.85
Human Site:
S2206
Identified Species:
29.7
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S2206
P
K
T
N
S
S
T
S
P
S
L
E
T
R
E
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
G2636
P
I
N
N
P
R
S
G
R
S
P
T
G
N
T
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
S2206
P
K
T
N
S
S
T
S
P
S
L
E
S
R
E
Dog
Lupus familis
XP_542202
2539
269675
S2443
T
K
T
N
S
S
T
S
P
S
L
E
S
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
S2176
S
K
T
N
S
S
T
S
P
S
L
E
S
R
D
Rat
Rattus norvegicus
P70478
2842
310514
V2657
A
V
S
R
T
E
D
V
W
V
R
I
E
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
V2658
A
V
S
K
T
E
D
V
W
V
R
I
E
D
C
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
V2651
A
V
S
K
T
E
D
V
W
V
R
I
E
D
C
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
V1998
P
I
K
G
T
E
K
V
A
S
A
P
S
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
S2260
T
S
P
T
H
R
A
S
K
L
P
T
K
K
G
Honey Bee
Apis mellifera
XP_624558
2760
306907
K2628
S
D
A
S
T
Y
K
K
D
T
I
D
I
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
S2789
I
H
S
S
S
R
H
S
S
S
Y
S
L
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
20
93.3
80
N.A.
80
0
N.A.
0
N.A.
0
13.3
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
26.6
100
86.6
N.A.
93.3
13.3
N.A.
13.3
N.A.
13.3
26.6
N.A.
13.3
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
9
0
0
0
9
0
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% C
% Asp:
0
9
0
0
0
0
25
0
9
0
0
9
0
25
17
% D
% Glu:
0
0
0
0
0
34
0
0
0
0
0
34
25
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
9
0
0
0
0
9
9
17
% G
% His:
0
9
0
0
9
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
17
0
0
0
0
0
0
0
0
9
25
9
0
0
% I
% Lys:
0
34
9
17
0
0
17
9
9
0
0
0
9
9
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
9
34
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
42
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
34
0
9
0
9
0
0
0
34
0
17
9
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
25
0
0
9
0
25
0
0
34
0
% R
% Ser:
17
9
34
17
42
34
9
50
9
59
0
9
34
17
9
% S
% Thr:
17
0
34
9
42
0
34
0
0
9
0
17
9
0
9
% T
% Val:
0
25
0
0
0
0
0
34
0
25
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _