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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
13.94
Human Site:
S2106
Identified Species:
27.88
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S2106
Y
A
S
L
P
H
I
S
V
A
R
R
P
D
G
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
S2536
R
R
T
G
S
S
S
S
I
L
S
A
S
S
E
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
S2106
Y
A
S
L
P
H
I
S
V
A
R
R
P
D
G
Dog
Lupus familis
XP_542202
2539
269675
H2343
K
R
Y
A
S
L
P
H
I
S
V
A
R
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
S2076
Y
A
S
L
P
H
I
S
V
S
R
R
S
D
S
Rat
Rattus norvegicus
P70478
2842
310514
S2557
E
H
S
K
H
S
S
S
L
P
R
V
S
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S2558
E
H
S
K
H
S
S
S
L
P
R
V
S
T
W
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
S2551
E
H
S
K
H
S
S
S
L
P
R
V
S
T
W
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
R1898
F
P
V
V
F
R
G
R
T
V
I
Y
T
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
R2160
A
T
A
V
K
L
V
R
G
R
K
K
P
A
Y
Honey Bee
Apis mellifera
XP_624558
2760
306907
K2528
K
N
K
Q
R
F
E
K
S
D
T
R
Q
W
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
T2689
Q
T
P
S
K
F
G
T
F
T
K
K
K
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
6.6
100
0
N.A.
80
20
N.A.
20
N.A.
20
0
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
20
100
13.3
N.A.
86.6
26.6
N.A.
26.6
N.A.
26.6
13.3
N.A.
40
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
9
9
0
0
0
0
0
17
0
17
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
0
25
0
% D
% Glu:
25
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% E
% Phe:
9
0
0
0
9
17
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
17
0
9
0
0
0
0
0
17
% G
% His:
0
25
0
0
25
25
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
25
0
17
0
9
0
0
0
0
% I
% Lys:
17
0
9
25
17
0
0
9
0
0
17
17
9
0
9
% K
% Leu:
0
0
0
25
0
17
0
0
25
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
0
25
0
9
0
0
25
0
0
25
9
9
% P
% Gln:
9
0
0
9
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
9
17
0
0
9
9
0
17
0
9
50
34
9
9
0
% R
% Ser:
0
0
50
9
17
34
34
59
9
17
9
0
42
9
9
% S
% Thr:
0
17
9
0
0
0
0
9
9
9
9
0
9
25
0
% T
% Val:
0
0
9
17
0
0
9
0
25
9
9
25
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
25
% W
% Tyr:
25
0
9
0
0
0
0
0
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _