KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
6.06
Human Site:
S1767
Identified Species:
12.12
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S1767
K
T
S
G
S
P
R
S
P
A
G
P
E
K
P
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
R2168
S
L
I
T
G
K
V
R
S
N
S
E
I
S
G
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
S1769
K
T
S
G
S
P
R
S
P
A
G
P
E
K
P
Dog
Lupus familis
XP_542202
2539
269675
E2012
Q
R
G
T
S
G
P
E
K
L
R
G
A
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
L1738
K
I
N
G
S
P
R
L
P
N
G
P
E
K
A
Rat
Rattus norvegicus
P70478
2842
310514
K2192
N
K
G
I
K
G
G
K
K
V
Y
K
S
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
K2193
N
K
G
I
K
G
G
K
K
V
Y
K
S
L
I
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
N2177
A
E
K
S
A
L
E
N
K
K
T
E
E
E
P
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
I1596
V
P
T
Q
R
L
L
I
Q
S
K
E
M
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
L1802
I
A
F
E
A
R
A
L
A
E
N
L
L
Q
P
Honey Bee
Apis mellifera
XP_624558
2760
306907
S2185
E
T
E
S
E
D
E
S
N
N
I
E
D
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
I2158
T
S
R
G
R
G
A
I
R
G
A
R
G
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
0
100
6.6
N.A.
66.6
0
N.A.
0
N.A.
13.3
0
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
0
100
20
N.A.
73.3
0
N.A.
0
N.A.
33.3
13.3
N.A.
20
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
17
0
17
0
9
17
9
0
9
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% D
% Glu:
9
9
9
9
9
0
17
9
0
9
0
34
34
9
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
25
34
9
34
17
0
0
9
25
9
9
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
9
17
0
0
0
17
0
0
9
0
9
0
17
% I
% Lys:
25
17
9
0
17
9
0
17
34
9
9
17
0
25
9
% K
% Leu:
0
9
0
0
0
17
9
17
0
9
0
9
9
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
17
0
9
0
0
0
0
9
9
25
9
0
0
0
0
% N
% Pro:
0
9
0
0
0
25
9
0
25
0
0
25
0
9
42
% P
% Gln:
9
0
0
9
0
0
0
0
9
0
0
0
0
17
0
% Q
% Arg:
0
9
9
0
17
9
25
9
9
0
9
9
0
0
0
% R
% Ser:
9
9
17
17
34
0
0
25
9
9
9
0
17
9
0
% S
% Thr:
9
25
9
17
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
9
0
0
0
0
0
9
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _