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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
10.61
Human Site:
S1716
Identified Species:
21.21
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S1716
E
A
S
S
E
S
D
S
I
L
S
F
V
S
G
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
D2095
L
S
R
Q
A
S
S
D
S
D
S
I
L
S
L
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
S1718
E
A
S
S
E
S
D
S
I
L
S
F
V
S
G
Dog
Lupus familis
XP_542202
2539
269675
S1964
E
A
S
S
G
S
D
S
G
P
S
E
S
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
D1686
L
E
A
S
S
E
S
D
S
L
L
S
L
V
S
Rat
Rattus norvegicus
P70478
2842
310514
S2130
C
L
S
R
Q
A
S
S
D
S
D
S
I
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
D2132
L
S
R
Q
A
S
S
D
S
D
S
I
L
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
L2123
Q
A
A
A
A
G
S
L
S
R
Q
G
S
S
D
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
V1548
N
K
E
T
Q
E
L
V
D
I
E
A
K
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
N1685
N
S
S
N
N
T
W
N
E
S
T
C
P
N
D
Honey Bee
Apis mellifera
XP_624558
2760
306907
S2114
L
L
D
C
E
T
I
S
L
V
S
N
E
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
D2066
P
S
S
M
E
D
D
D
S
S
P
A
N
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
20
100
53.3
N.A.
13.3
13.3
N.A.
20
N.A.
13.3
0
N.A.
6.6
26.6
N.A.
20
P-Site Similarity:
100
33.3
100
53.3
N.A.
26.6
33.3
N.A.
33.3
N.A.
33.3
20
N.A.
46.6
46.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
17
9
25
9
0
0
0
0
0
17
0
0
0
% A
% Cys:
9
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
9
0
0
9
34
34
17
17
9
0
0
0
17
% D
% Glu:
25
9
9
0
34
17
0
0
9
0
9
9
9
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% F
% Gly:
0
0
0
0
9
9
0
0
9
0
0
9
0
9
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
17
9
0
17
9
0
9
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
34
17
0
0
0
0
9
9
9
25
9
0
25
9
25
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
9
9
0
0
9
0
0
0
9
9
9
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
9
9
0
9
0
0
% P
% Gln:
9
0
0
17
17
0
0
0
0
0
9
0
0
9
0
% Q
% Arg:
0
0
17
9
0
0
0
0
0
9
0
0
0
9
0
% R
% Ser:
0
34
50
34
9
42
42
42
42
25
50
17
17
50
17
% S
% Thr:
0
0
0
9
0
17
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
9
0
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _