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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
9.7
Human Site:
S1679
Identified Species:
19.39
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S1679
A
A
G
S
D
R
A
S
D
L
D
S
V
E
W
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
P2058
D
S
E
H
G
L
S
P
D
S
E
N
F
D
W
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
S1681
A
A
G
S
D
R
A
S
D
L
D
S
V
E
W
Dog
Lupus familis
XP_542202
2539
269675
D1927
A
G
S
D
H
A
S
D
L
D
S
V
E
W
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
S1649
V
A
G
S
D
P
A
S
D
L
D
S
V
E
W
Rat
Rattus norvegicus
P70478
2842
310514
P2093
E
S
E
H
G
L
S
P
D
S
E
N
F
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
P2095
D
S
E
H
G
F
S
P
D
S
E
N
F
D
W
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
D2086
L
R
D
I
Q
S
P
D
S
E
N
A
F
S
P
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
T1511
Y
T
D
S
A
E
G
T
P
I
N
F
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
V1648
P
D
L
M
L
K
S
V
E
R
L
T
M
E
F
Honey Bee
Apis mellifera
XP_624558
2760
306907
E2077
S
T
H
N
I
E
S
E
I
Q
T
M
L
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
L2029
D
A
A
S
E
Q
A
L
L
D
E
C
I
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
13.3
100
6.6
N.A.
86.6
13.3
N.A.
13.3
N.A.
0
6.6
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
46.6
100
13.3
N.A.
86.6
46.6
N.A.
46.6
N.A.
13.3
26.6
N.A.
46.6
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
34
9
0
9
9
34
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
25
9
17
9
25
0
0
17
50
17
25
0
0
25
0
% D
% Glu:
9
0
25
0
9
17
0
9
9
9
34
0
9
42
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
9
34
0
9
% F
% Gly:
0
9
25
0
25
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
25
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
9
9
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
9
0
9
17
0
9
17
25
9
0
9
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
17
25
0
0
0
% N
% Pro:
9
0
0
0
0
9
9
25
9
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
9
9
0
0
0
9
0
0
0
0
9
% Q
% Arg:
0
9
0
0
0
17
0
0
0
9
0
0
0
0
9
% R
% Ser:
9
25
9
42
0
9
50
25
9
25
9
25
9
17
9
% S
% Thr:
0
17
0
0
0
0
0
9
0
0
9
9
0
9
9
% T
% Val:
9
0
0
0
0
0
0
9
0
0
0
9
25
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
50
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _