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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
7.58
Human Site:
S1645
Identified Species:
15.15
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S1645
P
R
R
R
P
P
V
S
G
L
R
R
R
K
P
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
H2024
P
S
R
L
K
G
D
H
E
K
Y
S
P
R
N
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
S1647
P
R
R
R
P
P
V
S
G
L
R
R
R
K
P
Dog
Lupus familis
XP_542202
2539
269675
S1893
P
R
R
R
L
Q
A
S
A
P
R
R
R
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
P1615
P
R
R
R
T
Q
V
P
G
S
R
R
R
K
P
Rat
Rattus norvegicus
P70478
2842
310514
G2059
P
S
R
L
K
G
E
G
E
W
Q
S
P
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
N2061
P
S
R
L
K
G
D
N
E
K
N
S
S
R
N
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
K2052
P
K
K
R
K
P
S
K
I
K
N
E
V
G
K
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
L1477
S
V
P
V
Y
M
V
L
Q
N
K
N
N
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
F1614
S
D
E
S
N
Q
S
F
I
M
E
T
M
V
R
Honey Bee
Apis mellifera
XP_624558
2760
306907
R2043
N
R
E
R
Y
R
T
R
T
L
N
D
S
E
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
R1995
G
I
N
K
D
S
R
R
V
F
A
T
E
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
13.3
100
66.6
N.A.
73.3
13.3
N.A.
13.3
N.A.
20
6.6
N.A.
0
20
N.A.
0
P-Site Similarity:
100
20
100
66.6
N.A.
73.3
26.6
N.A.
26.6
N.A.
33.3
20
N.A.
6.6
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
9
0
0
9
0
17
0
0
0
0
9
0
9
0
% D
% Glu:
0
0
17
0
0
0
9
0
25
0
9
9
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
25
0
9
25
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
17
0
0
0
0
0
0
% I
% Lys:
0
9
9
9
34
0
0
9
0
25
9
0
0
34
17
% K
% Leu:
0
0
0
25
9
0
0
9
0
25
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
9
0
0
9
0
9
% M
% Asn:
9
0
9
0
9
0
0
9
0
9
25
9
9
0
17
% N
% Pro:
67
0
9
0
17
25
0
9
0
9
0
0
17
0
34
% P
% Gln:
0
0
0
0
0
25
0
0
9
0
9
0
0
9
0
% Q
% Arg:
0
42
59
50
0
9
9
17
0
0
34
34
34
25
9
% R
% Ser:
17
25
0
9
0
9
17
25
0
9
0
25
17
0
0
% S
% Thr:
0
0
0
0
9
0
9
0
9
0
0
17
0
0
9
% T
% Val:
0
9
0
9
0
0
34
0
9
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _