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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
1.21
Human Site:
S1106
Identified Species:
2.42
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S1106
G
L
E
E
A
G
P
S
E
A
E
L
D
S
T
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
K1273
Q
I
A
E
I
K
E
K
I
G
T
R
S
A
E
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
G1108
G
L
E
E
A
G
P
G
E
A
E
L
D
S
V
Dog
Lupus familis
XP_542202
2539
269675
L1381
A
G
P
S
K
A
D
L
D
G
A
W
L
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
E1097
L
E
E
A
G
P
G
E
A
E
L
G
R
A
W
Rat
Rattus norvegicus
P70478
2842
310514
N1307
Q
I
A
E
I
K
E
N
D
V
T
R
S
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S1315
Q
I
T
E
L
K
E
S
A
G
A
G
S
T
E
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
E1315
L
Q
I
T
E
P
K
E
I
S
A
V
S
K
D
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
E986
H
P
S
A
R
P
T
E
Q
R
R
P
N
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
D1093
L
S
N
L
S
I
V
D
D
E
K
A
P
A
S
Honey Bee
Apis mellifera
XP_624558
2760
306907
N1377
I
H
N
D
L
I
D
N
D
Q
N
I
D
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
H1306
L
P
S
D
V
H
H
H
D
E
V
Q
E
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
6.6
86.6
0
N.A.
6.6
6.6
N.A.
13.3
N.A.
0
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
20
86.6
6.6
N.A.
13.3
33.3
N.A.
26.6
N.A.
13.3
13.3
N.A.
33.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
17
17
9
0
0
17
17
25
9
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
17
9
42
0
0
0
25
9
17
% D
% Glu:
0
9
25
42
9
0
25
25
17
25
17
0
9
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
9
0
0
9
17
9
9
0
25
0
17
0
9
0
% G
% His:
9
9
0
0
0
9
9
9
0
0
0
0
0
0
0
% H
% Ile:
9
25
9
0
17
17
0
0
17
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
9
25
9
9
0
0
9
0
0
17
0
% K
% Leu:
34
17
0
9
17
0
0
9
0
0
9
17
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
17
0
0
9
0
9
0
0
% N
% Pro:
0
17
9
0
0
25
17
0
0
0
0
9
9
0
17
% P
% Gln:
25
9
0
0
0
0
0
0
9
9
0
9
0
0
9
% Q
% Arg:
0
0
0
0
9
0
0
0
0
9
9
17
9
0
0
% R
% Ser:
0
9
17
9
9
0
0
17
0
9
0
0
34
17
9
% S
% Thr:
0
0
9
9
0
0
9
0
0
0
17
0
0
17
9
% T
% Val:
0
0
0
0
9
0
9
0
0
9
9
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _