KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECD
All Species:
31.21
Human Site:
Y93
Identified Species:
57.22
UniProt:
O95905
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95905
NP_001129225.1
644
72758
Y93
E
D
E
W
F
I
V
Y
V
I
K
Q
I
T
K
Chimpanzee
Pan troglodytes
XP_508169
648
72940
Y93
E
D
E
W
F
I
V
Y
V
I
K
Q
I
T
K
Rhesus Macaque
Macaca mulatta
XP_001103459
644
72818
Y93
E
D
E
W
F
I
V
Y
V
I
K
Q
I
T
K
Dog
Lupus familis
XP_536386
643
72587
Y93
E
D
E
W
F
I
V
Y
I
V
K
Q
I
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CS74
641
71691
Y93
E
D
E
W
F
I
V
Y
V
I
K
Q
I
T
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508376
598
66758
Y93
E
D
E
W
F
I
V
Y
L
I
Q
Q
I
T
K
Chicken
Gallus gallus
XP_421522
638
71575
I93
I
V
Y
L
V
R
E
I
S
R
A
F
P
E
L
Frog
Xenopus laevis
NP_001088274
642
71779
Y93
E
D
E
W
F
I
V
Y
L
V
Q
Q
I
T
K
Zebra Danio
Brachydanio rerio
XP_002665219
632
70256
K95
W
F
I
V
Y
L
L
K
H
I
T
H
T
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W032
684
77889
Y118
S
D
E
W
F
V
V
Y
L
L
T
E
I
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786801
567
62710
N74
F
P
A
K
V
Q
S
N
F
H
H
T
H
C
L
Poplar Tree
Populus trichocarpa
XP_002326322
639
72489
F94
E
D
E
W
F
T
V
F
L
L
F
Q
I
S
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSM5
643
73143
F100
E
D
E
W
F
A
V
F
L
L
F
R
I
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
95.9
86.6
N.A.
78.4
N.A.
N.A.
59.4
59.3
60
52.6
N.A.
29.6
N.A.
N.A.
21.2
Protein Similarity:
100
97.3
97.9
92.6
N.A.
89.1
N.A.
N.A.
73.1
72.9
75.6
69.8
N.A.
49.5
N.A.
N.A.
36.6
P-Site Identity:
100
100
100
86.6
N.A.
100
N.A.
N.A.
86.6
0
80
6.6
N.A.
53.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
0
100
26.6
N.A.
86.6
N.A.
N.A.
0
Percent
Protein Identity:
34
N.A.
N.A.
35.4
N.A.
N.A.
Protein Similarity:
55.2
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
53.3
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
80
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
70
0
77
0
0
0
8
0
0
0
0
8
0
8
0
% E
% Phe:
8
8
0
0
77
0
0
16
8
0
16
8
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
8
8
8
0
8
% H
% Ile:
8
0
8
0
0
54
0
8
8
47
0
0
77
0
0
% I
% Lys:
0
0
0
8
0
0
0
8
0
0
39
0
0
0
54
% K
% Leu:
0
0
0
8
0
8
8
0
39
24
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
16
62
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
8
% R
% Ser:
8
0
0
0
0
0
8
0
8
0
0
0
0
16
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
16
8
8
62
8
% T
% Val:
0
8
0
8
16
8
77
0
31
16
0
0
0
0
0
% V
% Trp:
8
0
0
77
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _