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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECD
All Species:
20.61
Human Site:
Y64
Identified Species:
37.78
UniProt:
O95905
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95905
NP_001129225.1
644
72758
Y64
N
Q
P
F
N
L
K
Y
K
P
G
K
G
G
V
Chimpanzee
Pan troglodytes
XP_508169
648
72940
Y64
N
Q
P
F
N
L
K
Y
K
P
G
K
G
G
V
Rhesus Macaque
Macaca mulatta
XP_001103459
644
72818
Y64
N
Q
P
F
N
L
K
Y
K
P
G
K
G
S
V
Dog
Lupus familis
XP_536386
643
72587
Y64
N
Q
P
F
N
L
R
Y
K
P
G
K
G
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CS74
641
71691
Y64
N
Q
P
F
N
L
K
Y
K
P
A
K
G
G
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508376
598
66758
C64
N
Q
P
F
N
L
K
C
Q
P
G
K
D
D
V
Chicken
Gallus gallus
XP_421522
638
71575
G64
L
R
Y
V
P
P
C
G
D
T
P
E
H
I
G
Frog
Xenopus laevis
NP_001088274
642
71779
Y64
N
Q
P
F
N
L
R
Y
K
A
K
K
G
D
T
Zebra Danio
Brachydanio rerio
XP_002665219
632
70256
E66
F
N
L
T
Q
H
P
E
K
G
D
V
P
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W032
684
77889
E89
N
E
E
T
N
P
E
E
E
A
E
L
G
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786801
567
62710
K45
H
A
V
E
V
V
R
K
H
S
Q
K
T
L
A
Poplar Tree
Populus trichocarpa
XP_002326322
639
72489
L65
H
E
P
F
S
L
S
L
S
S
S
S
S
P
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSM5
643
73143
S71
L
S
I
A
L
S
S
S
C
A
C
T
N
T
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
95.9
86.6
N.A.
78.4
N.A.
N.A.
59.4
59.3
60
52.6
N.A.
29.6
N.A.
N.A.
21.2
Protein Similarity:
100
97.3
97.9
92.6
N.A.
89.1
N.A.
N.A.
73.1
72.9
75.6
69.8
N.A.
49.5
N.A.
N.A.
36.6
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
N.A.
N.A.
73.3
0
66.6
6.6
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
80
13.3
73.3
6.6
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
34
N.A.
N.A.
35.4
N.A.
N.A.
Protein Similarity:
55.2
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
24
8
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
8
8
8
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
8
0
8
24
0
% D
% Glu:
0
16
8
8
0
0
8
16
8
0
8
8
0
0
0
% E
% Phe:
8
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
39
0
54
24
8
% G
% His:
16
0
0
0
0
8
0
0
8
0
0
0
8
0
8
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
39
8
54
0
8
62
0
0
0
% K
% Leu:
16
0
8
0
8
62
0
8
0
0
0
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
62
8
0
0
62
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
62
0
8
16
8
0
0
47
8
0
8
8
8
% P
% Gln:
0
54
0
0
8
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
24
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
8
16
8
8
16
8
8
8
8
0
% S
% Thr:
0
0
0
16
0
0
0
0
0
8
0
8
8
8
8
% T
% Val:
0
0
8
8
8
8
0
0
0
0
0
8
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _