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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECD
All Species:
9.09
Human Site:
T451
Identified Species:
16.67
UniProt:
O95905
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95905
NP_001129225.1
644
72758
T451
K
E
Q
N
Y
D
L
T
E
V
S
E
S
M
K
Chimpanzee
Pan troglodytes
XP_508169
648
72940
T455
K
E
Q
N
Y
D
L
T
Q
V
S
E
S
M
K
Rhesus Macaque
Macaca mulatta
XP_001103459
644
72818
T451
K
E
Q
N
Y
D
L
T
Q
V
S
E
S
M
K
Dog
Lupus familis
XP_536386
643
72587
N450
E
E
Q
N
Y
D
L
N
Q
V
S
E
S
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CS74
641
71691
D449
K
E
E
L
Q
N
Y
D
V
A
Q
V
S
D
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508376
598
66758
E405
F
E
S
L
T
S
D
E
D
L
D
P
E
T
Q
Chicken
Gallus gallus
XP_421522
638
71575
V445
Q
K
Y
D
L
E
A
V
A
E
S
M
K
A
F
Frog
Xenopus laevis
NP_001088274
642
71779
E449
E
Q
K
Y
N
L
S
E
V
T
E
S
M
K
A
Zebra Danio
Brachydanio rerio
XP_002665219
632
70256
E436
G
G
R
G
G
T
G
E
E
V
Q
E
E
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W032
684
77889
E490
G
I
E
H
R
G
L
E
E
P
E
L
D
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786801
567
62710
V375
G
G
G
G
M
E
D
V
A
F
N
P
E
E
F
Poplar Tree
Populus trichocarpa
XP_002326322
639
72489
A427
N
E
M
D
L
Y
N
A
K
H
K
K
K
Q
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSM5
643
73143
G447
G
K
E
K
Q
E
A
G
S
S
S
D
A
N
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
95.9
86.6
N.A.
78.4
N.A.
N.A.
59.4
59.3
60
52.6
N.A.
29.6
N.A.
N.A.
21.2
Protein Similarity:
100
97.3
97.9
92.6
N.A.
89.1
N.A.
N.A.
73.1
72.9
75.6
69.8
N.A.
49.5
N.A.
N.A.
36.6
P-Site Identity:
100
93.3
93.3
80
N.A.
20
N.A.
N.A.
6.6
6.6
0
20
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
N.A.
N.A.
26.6
33.3
20
26.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
34
N.A.
N.A.
35.4
N.A.
N.A.
Protein Similarity:
55.2
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
8
16
8
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
0
31
16
8
8
0
8
8
8
8
8
% D
% Glu:
16
54
24
0
0
24
0
31
24
8
16
39
24
16
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% F
% Gly:
31
16
8
16
8
8
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
31
16
8
8
0
0
0
0
8
0
8
8
16
8
31
% K
% Leu:
0
0
0
16
16
8
39
0
0
8
0
8
0
0
0
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
8
8
31
16
% M
% Asn:
8
0
0
31
8
8
8
8
0
0
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
16
0
0
0
% P
% Gln:
8
8
31
0
16
0
0
0
24
0
16
0
0
8
8
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
8
8
0
8
8
47
8
39
8
16
% S
% Thr:
0
0
0
0
8
8
0
24
0
8
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
16
16
39
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
31
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _