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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECD
All Species:
24.55
Human Site:
S609
Identified Species:
45
UniProt:
O95905
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95905
NP_001129225.1
644
72758
S609
S
N
I
L
E
S
Y
S
S
Q
A
G
L
A
G
Chimpanzee
Pan troglodytes
XP_508169
648
72940
S613
S
N
I
L
E
S
Y
S
S
Q
A
G
L
A
G
Rhesus Macaque
Macaca mulatta
XP_001103459
644
72818
S609
S
N
I
L
E
S
Y
S
S
Q
A
G
L
A
G
Dog
Lupus familis
XP_536386
643
72587
S608
S
N
I
L
E
S
Y
S
S
Q
A
G
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CS74
641
71691
S607
L
I
S
N
I
L
E
S
Y
S
S
Q
A
G
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508376
598
66758
I563
D
A
N
L
V
S
N
I
L
E
S
Y
H
S
Q
Chicken
Gallus gallus
XP_421522
638
71575
S603
T
N
L
L
E
S
Y
S
A
Q
A
G
L
A
G
Frog
Xenopus laevis
NP_001088274
642
71779
S607
T
N
L
L
E
S
Y
S
S
Q
A
G
L
A
G
Zebra Danio
Brachydanio rerio
XP_002665219
632
70256
L594
I
Q
P
L
D
V
D
L
N
L
V
T
N
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W032
684
77889
Q648
R
N
M
M
D
S
Y
Q
S
Q
V
G
G
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786801
567
62710
I533
D
V
N
L
L
K
N
I
L
E
S
Y
S
S
Q
Poplar Tree
Populus trichocarpa
XP_002326322
639
72489
T585
K
N
E
E
T
S
N
T
M
E
G
M
D
E
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSM5
643
73143
N605
T
P
V
D
A
D
F
N
L
V
K
N
L
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
95.9
86.6
N.A.
78.4
N.A.
N.A.
59.4
59.3
60
52.6
N.A.
29.6
N.A.
N.A.
21.2
Protein Similarity:
100
97.3
97.9
92.6
N.A.
89.1
N.A.
N.A.
73.1
72.9
75.6
69.8
N.A.
49.5
N.A.
N.A.
36.6
P-Site Identity:
100
100
100
100
N.A.
6.6
N.A.
N.A.
13.3
80
86.6
6.6
N.A.
53.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
13.3
N.A.
N.A.
33.3
100
100
20
N.A.
73.3
N.A.
N.A.
26.6
Percent
Protein Identity:
34
N.A.
N.A.
35.4
N.A.
N.A.
Protein Similarity:
55.2
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
8
0
47
0
8
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
16
8
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
8
8
47
0
8
0
0
24
0
0
0
8
16
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
54
8
8
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
8
31
0
8
0
0
16
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
0
16
70
8
8
0
8
24
8
0
0
54
16
16
% L
% Met:
0
0
8
8
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
62
16
8
0
0
24
8
8
0
0
8
8
0
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
54
0
8
0
0
16
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
31
0
8
0
0
70
0
54
47
8
24
0
8
16
0
% S
% Thr:
24
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% T
% Val:
0
8
8
0
8
8
0
0
0
8
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
54
0
8
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _