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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
20.61
Human Site:
T490
Identified Species:
32.38
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
T490
A
T
T
V
T
A
I
T
P
A
P
I
Q
Q
P
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
T490
A
T
T
V
T
A
I
T
P
A
P
I
Q
Q
P
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
L242
L
T
P
S
R
N
S
L
N
V
D
L
Y
D
L
Dog
Lupus familis
XP_534537
1097
121903
P477
T
A
V
G
P
S
H
P
A
W
V
P
A
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
T489
A
T
T
V
T
A
I
T
P
A
P
I
Q
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
T481
A
T
T
V
T
A
I
T
P
A
P
I
Q
Q
P
Chicken
Gallus gallus
XP_419666
1136
127431
T496
A
T
T
V
T
A
I
T
P
A
P
I
Q
Q
P
Frog
Xenopus laevis
NP_001087838
1118
125984
S485
T
V
T
A
V
T
P
S
P
I
Q
Q
P
V
K
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
T476
T
A
Y
Q
E
P
P
T
P
P
A
P
A
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
Q479
A
T
V
V
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
Honey Bee
Apis mellifera
XP_395146
1137
124999
P526
M
H
H
P
V
P
P
P
P
Y
G
T
A
T
T
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
V566
P
Y
R
P
A
A
P
V
Q
S
V
E
M
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
Q189
L
R
S
V
K
S
F
Q
R
L
Q
Q
E
Q
E
Red Bread Mold
Neurospora crassa
P38679
598
67999
T31
T
Y
P
T
T
P
S
T
F
P
Q
P
V
F
P
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
0
N.A.
100
N.A.
N.A.
100
100
13.3
13.3
N.A.
33.3
6.6
0
6.6
P-Site Similarity:
100
100
13.3
6.6
N.A.
100
N.A.
N.A.
100
100
20
13.3
N.A.
33.3
6.6
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
14
0
7
7
40
0
0
7
34
7
0
20
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
0
7
7
0
14
% E
% Phe:
0
0
0
0
0
0
7
0
7
0
0
0
0
7
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
7
7
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
34
0
0
7
0
34
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
7
% K
% Leu:
14
0
0
0
0
0
0
7
0
7
0
7
0
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
14
14
7
20
27
14
54
14
34
20
7
7
40
% P
% Gln:
0
0
0
7
7
7
7
14
14
7
27
20
40
47
7
% Q
% Arg:
0
7
7
0
7
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
0
0
7
7
0
14
14
7
0
7
0
0
0
0
0
% S
% Thr:
27
47
40
7
40
7
0
47
0
0
0
7
0
7
20
% T
% Val:
0
7
14
47
14
0
0
7
0
7
14
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
14
7
0
0
0
0
0
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _