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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 9.7
Human Site: S593 Identified Species: 15.24
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S593 S L P K E D E S E K S Y E N V
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S593 S L P K E D E S E K S Y E N V
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 V345 R P E P Q T A V G P S H P A W
Dog Lupus familis XP_534537 1097 121903 K580 D K A G K D K K Q I Q T S P V
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 S592 S L P K E D D S E K S A D S G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 E584 V A K D E E G E K T H D N F D
Chicken Gallus gallus XP_419666 1136 127431 N599 I S S K E E E N E K N Y E C V
Frog Xenopus laevis NP_001087838 1118 125984 T588 E K N I E A T T G I T E K K Q
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 F579 P M Y S P Q A F K F F M E Q H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 P582 S N L A T T P P I P P A K Y N
Honey Bee Apis mellifera XP_395146 1137 124999 G629 N N H S P D N G A K G A G S S
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529 Q12 A P E M E I S Q Y T K D K A S
Sea Urchin Strong. purpuratus XP_795100 1199 133231 G669 I S E I S D V G D L E S A S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 N292 A V K L K I E N F Y Q S S V K
Red Bread Mold Neurospora crassa P38679 598 67999 N134 F A P A P E R N P D K Y G P N
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 6.6 13.3 N.A. 66.6 N.A. N.A. 6.6 53.3 6.6 6.6 N.A. 6.6 13.3 6.6 6.6
P-Site Similarity: 100 100 20 33.3 N.A. 86.6 N.A. N.A. 20 73.3 26.6 20 N.A. 13.3 26.6 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 14 7 14 0 7 14 0 7 0 0 20 7 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 7 0 0 7 0 40 7 0 7 7 0 14 7 0 7 % D
% Glu: 7 0 20 0 47 20 27 7 27 0 7 7 27 0 0 % E
% Phe: 7 0 0 0 0 0 0 7 7 7 7 0 0 7 0 % F
% Gly: 0 0 0 7 0 0 7 14 14 0 7 0 14 0 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 7 7 0 0 7 % H
% Ile: 14 0 0 14 0 14 0 0 7 14 0 0 0 0 0 % I
% Lys: 0 14 14 27 14 0 7 7 14 34 14 0 20 7 7 % K
% Leu: 0 20 7 7 0 0 0 0 0 7 0 0 0 0 0 % L
% Met: 0 7 0 7 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 7 14 7 0 0 0 7 20 0 0 7 0 7 14 14 % N
% Pro: 7 14 27 7 20 0 7 7 7 14 7 0 7 14 0 % P
% Gln: 0 0 0 0 7 7 0 7 7 0 14 0 0 7 7 % Q
% Arg: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 27 14 7 14 7 0 7 20 0 0 27 14 14 20 20 % S
% Thr: 0 0 0 0 7 14 7 7 0 14 7 7 0 0 0 % T
% Val: 7 7 0 0 0 0 7 7 0 0 0 0 0 7 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 7 0 0 0 0 0 7 7 0 27 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _