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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 6.06
Human Site: S404 Identified Species: 9.52
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S404 P S S Y T N G S I P Q S M M V
Chimpanzee Pan troglodytes XP_001173355 1130 126853 N404 P S S Y T N G N I P Q S M M V
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 V156 G E P L G Y G V Q R S P S F Q
Dog Lupus familis XP_534537 1097 121903 K391 S R R D S L Q K P G L E A P A
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 N403 P P S F A N G N V P Q S M M V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 T395 P S P Y A N G T V P Q S L M V
Chicken Gallus gallus XP_419666 1136 127431 N410 P S A Y T N G N L P P T M L V
Frog Xenopus laevis NP_001087838 1118 125984 N399 N A Y G T N T N L P P S M L V
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 P390 V Q Q A Q T P P G Q D T S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 S393 V A P Q S P S S A S A S N S P
Honey Bee Apis mellifera XP_395146 1137 124999 Y440 T P P P P P S Y A S S I Q Q K
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529
Sea Urchin Strong. purpuratus XP_795100 1199 133231 G480 G G Q Q Q R G G T P T M T Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 S103 P H N N Y A A S N Q M I N T P
Red Bread Mold Neurospora crassa P38679 598 67999
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 93.3 6.6 0 N.A. 66.6 N.A. N.A. 66.6 60 40 0 N.A. 13.3 0 0 13.3
P-Site Similarity: 100 100 6.6 6.6 N.A. 86.6 N.A. N.A. 86.6 93.3 66.6 6.6 N.A. 26.6 0 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 7 7 14 7 7 0 14 0 7 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 14 7 0 7 7 0 47 7 7 7 0 0 0 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 14 0 0 14 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % K
% Leu: 0 0 0 7 0 7 0 0 14 0 7 0 7 14 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 7 34 27 0 % M
% Asn: 7 0 7 7 0 40 0 27 7 0 0 0 14 0 0 % N
% Pro: 40 14 27 7 7 14 7 7 7 47 14 7 0 7 14 % P
% Gln: 0 7 14 14 14 0 7 0 7 14 27 0 7 14 14 % Q
% Arg: 0 7 7 0 0 7 0 0 0 7 0 0 0 0 0 % R
% Ser: 7 27 20 0 14 0 14 20 0 14 14 40 14 14 7 % S
% Thr: 7 0 0 0 27 7 7 7 7 0 7 14 7 7 0 % T
% Val: 14 0 0 0 0 0 0 7 14 0 0 0 0 0 40 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 27 7 7 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _