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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML2
All Species:
35.76
Human Site:
S423
Identified Species:
65.56
UniProt:
O95834
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95834
NP_036287.1
649
70679
S423
I
I
E
D
P
A
R
S
A
G
F
H
P
S
G
Chimpanzee
Pan troglodytes
XP_001165936
649
70646
S423
I
I
E
D
P
A
R
S
A
G
F
H
P
S
G
Rhesus Macaque
Macaca mulatta
XP_001110928
815
88569
S589
I
I
E
D
P
A
R
S
A
G
F
H
P
S
G
Dog
Lupus familis
XP_852371
649
70597
S423
I
I
E
D
P
A
R
S
A
G
F
H
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNG5
649
70715
S423
S
I
E
D
P
A
R
S
A
G
F
H
P
S
G
Rat
Rattus norvegicus
Q6P6T4
649
70692
S423
S
I
E
D
P
A
R
S
A
G
F
H
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
A634
I
I
E
D
P
A
Q
A
S
G
F
H
P
S
G
Chicken
Gallus gallus
XP_421362
815
90017
S589
I
I
E
D
P
A
Q
S
S
G
F
H
P
S
A
Frog
Xenopus laevis
Q2TAF3
927
102313
C580
V
L
D
E
P
G
H
C
A
D
F
H
P
T
G
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
S579
A
I
E
D
P
A
R
S
V
G
F
H
P
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
A849
G
Y
E
C
V
A
L
A
F
H
P
F
G
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
S664
I
D
K
K
V
E
F
S
K
K
F
I
D
S
V
Sea Urchin
Strong. purpuratus
Q26613
686
75435
S460
L
M
E
D
G
C
Q
S
A
G
F
H
P
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.7
97.3
N.A.
94.9
93.9
N.A.
51.8
54.4
41.7
57.6
N.A.
23.7
N.A.
23.5
53.9
Protein Similarity:
100
100
79.5
99
N.A.
97.6
97.2
N.A.
63.1
66.6
55.2
68.8
N.A.
35.8
N.A.
40.1
71.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
80
40
86.6
N.A.
13.3
N.A.
26.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
93.3
73.3
86.6
N.A.
26.6
N.A.
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
77
0
16
62
0
0
0
0
0
8
% A
% Cys:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
77
0
0
0
0
0
8
0
0
8
0
0
% D
% Glu:
0
0
85
8
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
93
8
0
0
0
% F
% Gly:
8
0
0
0
8
8
0
0
0
77
0
0
8
0
77
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
85
0
0
0
% H
% Ile:
54
70
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
8
0
0
0
0
8
8
0
0
0
0
0
% K
% Leu:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
77
0
0
0
0
0
8
0
85
0
0
% P
% Gln:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
0
0
0
0
0
77
16
0
0
0
0
85
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% T
% Val:
8
0
0
0
16
0
0
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _