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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM50A
All Species:
28.79
Human Site:
Y119
Identified Species:
52.78
UniProt:
O95807
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95807
NP_055128.1
157
17400
Y119
M
W
I
L
F
G
G
Y
V
A
K
E
K
D
I
Chimpanzee
Pan troglodytes
XP_001137896
126
13977
P98
T
E
K
D
I
V
Y
P
G
I
A
V
F
F
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535354
157
17353
Y119
M
W
I
L
F
G
G
Y
V
A
K
E
K
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXL1
157
17477
Y119
M
W
I
L
F
G
G
Y
V
A
K
E
K
D
V
Rat
Rattus norvegicus
NP_001120997
157
17375
Y119
M
W
I
L
F
G
G
Y
V
A
K
E
K
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510935
157
17397
Y119
M
W
I
L
F
G
G
Y
V
V
K
E
K
A
A
Chicken
Gallus gallus
XP_001232925
196
21690
Y158
M
W
I
L
F
G
G
Y
V
V
K
E
K
A
V
Frog
Xenopus laevis
NP_001089470
157
17318
Y119
M
W
I
L
F
G
G
Y
V
A
N
G
N
P
V
Zebra Danio
Brachydanio rerio
NP_998694
164
18145
F122
M
W
I
L
F
G
G
F
V
V
T
G
T
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647888
152
16919
K119
D
F
I
N
N
E
K
K
D
G
W
F
G
V
A
Honey Bee
Apis mellifera
XP_624182
155
17167
F119
C
W
I
L
F
A
D
F
V
A
V
G
A
Q
H
Nematode Worm
Caenorhab. elegans
NP_490985
157
17388
Y118
T
W
I
L
F
S
D
Y
V
L
I
Q
G
S
H
Sea Urchin
Strong. purpuratus
XP_783010
165
18104
Y122
M
W
I
L
F
E
D
Y
V
V
N
P
K
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
N.A.
96.8
N.A.
94.2
94.2
N.A.
93.6
65.8
86.6
84.7
N.A.
37.5
49.6
44.5
65.4
Protein Similarity:
100
80.2
N.A.
99.3
N.A.
96.8
97.4
N.A.
97.4
72.9
93.6
91.4
N.A.
55.4
66.8
64.9
77.5
P-Site Identity:
100
0
N.A.
93.3
N.A.
93.3
93.3
N.A.
80
80
66.6
53.3
N.A.
6.6
40
40
53.3
P-Site Similarity:
100
0
N.A.
93.3
N.A.
100
93.3
N.A.
80
86.6
73.3
66.6
N.A.
13.3
46.6
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
47
8
0
8
31
16
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
24
0
8
0
0
0
0
16
0
% D
% Glu:
0
8
0
0
0
16
0
0
0
0
0
47
0
8
0
% E
% Phe:
0
8
0
0
85
0
0
16
0
0
0
8
8
8
0
% F
% Gly:
0
0
0
0
0
62
62
0
8
8
0
24
16
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% H
% Ile:
0
0
93
0
8
0
0
0
0
8
8
0
0
0
24
% I
% Lys:
0
0
8
0
0
0
8
8
0
0
47
0
54
0
0
% K
% Leu:
0
0
0
85
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
16
0
8
8
8
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% S
% Thr:
16
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
85
31
8
8
0
8
24
% V
% Trp:
0
85
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _