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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGF19 All Species: 6.97
Human Site: Y154 Identified Species: 19.17
UniProt: O95750 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95750 NP_005108.1 216 24003 Y154 S A K Q R Q L Y K N R G F L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100825 216 23988 Y154 S A K Q R Q L Y K N R G F L P
Dog Lupus familis XP_540802 256 27819 E190 T K I G L V M E Y R T T Q G R
Cat Felis silvestris
Mouse Mus musculus O35622 218 25217 L161 Q A K P R E Q L Q D Q K P S N
Rat Rattus norvegicus Q8VI82 251 27893 P147 R S K R I F Q P G T N P P P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506714 272 30387 F207 S A K Q R Q Q F K G R D F L P
Chicken Gallus gallus P48801 220 25031 E152 T K R K A S A E R L W Y V S V
Frog Xenopus laevis P12226 155 17223 C101 L R C I T D E C F F F E R L E
Zebra Danio Brachydanio rerio P48802 256 28905 S174 G S K R R A S S K R Q W Y V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 62.8 N.A. 52.7 29.4 N.A. 45.2 25.4 25 23 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 98.1 67.5 N.A. 68.3 41 N.A. 56.2 40 40.7 37.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 0 N.A. 20 6.6 N.A. 73.3 0 6.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 13.3 N.A. 46.6 20 N.A. 80 26.6 6.6 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 45 0 0 12 12 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 12 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 0 12 0 12 0 0 0 % D
% Glu: 0 0 0 0 0 12 12 23 0 0 0 12 0 0 12 % E
% Phe: 0 0 0 0 0 12 0 12 12 12 12 0 34 0 12 % F
% Gly: 12 0 0 12 0 0 0 0 12 12 0 23 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 12 12 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 23 67 12 0 0 0 0 45 0 0 12 0 0 0 % K
% Leu: 12 0 0 0 12 0 23 12 0 12 0 0 0 45 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 23 12 0 0 0 12 % N
% Pro: 0 0 0 12 0 0 0 12 0 0 0 12 23 12 34 % P
% Gln: 12 0 0 34 0 34 34 0 12 0 23 0 12 0 0 % Q
% Arg: 12 12 12 23 56 0 0 0 12 23 34 0 12 0 12 % R
% Ser: 34 23 0 0 0 12 12 12 0 0 0 0 0 23 12 % S
% Thr: 23 0 0 0 12 0 0 0 0 12 12 12 0 0 0 % T
% Val: 0 0 0 0 0 12 0 0 0 0 0 0 12 12 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 23 12 0 0 12 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _